Multi-Scale Applications of Neutron Scattering and Imaging

Hassina Bilheux, John Katsaras, Chris Stanley, Arvind Ramanathan, Dean Myles, Maria Cekanova

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Neutron scattering and imaging are exquisitely sensitive to differences i. The bulk hydrogen content of biological materials. This provides a unique, natural contrast between common classes of biomolecules that can be used to distinguis. The individual components of complex biological assemblies, membranes and multicellular tissue systems. Applications in human biology range from atomic-resolution analysis of hydrogen atoms in enzymes, through to multi-scale analysis of hierarchical structures and assemblies involved in disease and extend to sub-millimeter resolution imaging of tissues and organs. The completion o. The Spallation Neutron Source (SNS) an. The upgrade o. The High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory (ORNL) provide access to a powerful new suite of instruments that can examine biological structure and function across multiple levels of organization that spanning from molecules to living cells and tissues.

Original languageEnglish
Title of host publicationProceedings of the 2014 Biomedical Sciences and Engineering Conference - 5th Annual ORNL Biomedical Sciences and Engineering Conference
Subtitle of host publicationCollaborative Biomedical Innovations - The Multi-Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, BSEC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479941599
DOIs
StatePublished - Jul 29 2014
Event5th Annual ORNL Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations, BSEC 2014 - Oak Ridge, United States
Duration: May 6 2014May 8 2014

Publication series

NameProceedings of the 2014 Biomedical Sciences and Engineering Conference - 5th Annual ORNL Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations - The Multi-Scale Brain: Spanning Molecular, Cellular, Systems, Cognitive, Behavioral, and Clinical Neuroscience, BSEC 2014

Conference

Conference5th Annual ORNL Biomedical Sciences and Engineering Conference: Collaborative Biomedical Innovations, BSEC 2014
Country/TerritoryUnited States
CityOak Ridge
Period05/6/1405/8/14

Keywords

  • Neutron
  • amyloid
  • biomembrane
  • diffraction
  • disease
  • imaging
  • protein complexes
  • scattering
  • tissue

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