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Multi-Label Classification with Constraint-Based Learning for Hierarchical Consistency

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We explore the limitations of traditional crossentropy loss in a hierarchical multi-label classification setting and introduce a novel loss function. This function is designed to integrate hierarchical constraints directly into the training process. By incorporating such constraints into the loss, our approach slightly improves the logical consistency of predictions in structured domains. We demonstrate the efficacy of our approach through experiments on primary site and histology classification by using electronic pathology reports. These results show that our proposed hierarchical loss function enhances the model's ability to produce predictions that are logically consistent with the natural data hierarchies, and it slightly improves predictive accuracy. Our framework may be extended to other hierarchical domains, however the performance gains are context specific.

Original languageEnglish
Title of host publicationProceedings - 2025 IEEE Conference on Artificial Intelligence, CAI 2025
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages537-542
Number of pages6
ISBN (Electronic)9798331524005
DOIs
StatePublished - 2025
Event3rd IEEE Conference on Artificial Intelligence, CAI 2025 - Santa Clara, United States
Duration: May 5 2025May 7 2025

Publication series

NameProceedings - 2025 IEEE Conference on Artificial Intelligence, CAI 2025

Conference

Conference3rd IEEE Conference on Artificial Intelligence, CAI 2025
Country/TerritoryUnited States
CitySanta Clara
Period05/5/2505/7/25

Funding

This work has been supported in part by the Joint Design of Advanced Computing Solutions for Cancer program established by the US Department of Energy (DOE) and the NCI of the National Institutes of Health. This work was performed under the auspices of the DOE by Argonne National Laboratory under Contract DE-AC02-06-CH11357, Lawrence Livermore National Laboratory under Contract DEAC52- 07NA27344, Los Alamos National Laboratory under Contract DE-AC5206NA25396, and Oak Ridge National Laboratory under Contract DE-AC05-00OR22725. The authors gratefully acknowledge Xiao-Cheng Wu of the Louisiana Tumor Registry for curating and providing the data. The authors would also like to acknowledge contributions to this study by other staff members in the participating central cancer registries. These registries are supported by the NCI s SEER program, the Centers for Disease Control and Prevention s National Program of Cancer Registries (NPCR), and/or state agencies, universities, and cancer centers. The participating central cancer registries include the following: Public Health Institute, SEER HHSN261201800009I Louisiana Tumor Registry, SEER HHSN261201800007I and HHSN26100002 and NPCR NU58DP0063.

Keywords

  • Hierarchical classification
  • artificial intelligence
  • constraint-based learning
  • electronic health records
  • machine learning
  • multitask learning

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