TY - JOUR
T1 - MR Performance Comparison of a PET/MR System Before and After SiPM-Based Time-of-Flight PET Detector Insertion
AU - Khalighi, Mohammad Mehdi
AU - Delso, Gaspar
AU - Maramraju, Sri Harsha
AU - Deller, Timothy W.
AU - Levin, Craig S.
AU - Glover, Gary H.
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2016/10
Y1 - 2016/10
N2 - A silicon photomultiplier (SiPM)-based time-of-flight capable PET detector has been integrated with a 70 cm wide-bore 3T MR scanner for simultaneous whole-body imaging (MR750w, GE Healthcare, Waukesha, WI). After insertion of the PET detector, the final PET/MR bore is 60 cm wide (SIGNA PET/MR, GE Healthcare, Waukesha, WI). The MR performance was compared before and after the PET ring insertion. B0 homogeneity, B+1 uniformity of the body coil along with peak B+1, coherent noise, and FBIRN (Function Biomedical Informatics Research Network) tests are used to compare the MR performance. It is shown that B0 homogeneity and coherent noise have not changed according to the system specifications. Peak B+1 is increased by 33% and B+1 inhomogeneity is increased by 4% after PET ring insertion due to a smaller diameter body coil design. The FBIRN test shows similar temporal stability before and after PET ring insertion. Due to a smaller body coil on the PET/MR system, the signal fluctuation to noise ratio (SFNR) and SNR for body receive coil, are improved by ∼40% and ∼160% for Echo Planar Imaging (EPI) and spiral sequences respectively. Comparison using RF and gradient-intensive clinical sequences shows inserting the PET detectors into the wide-bore MRI has not compromised the MR image quality according to these tests.
AB - A silicon photomultiplier (SiPM)-based time-of-flight capable PET detector has been integrated with a 70 cm wide-bore 3T MR scanner for simultaneous whole-body imaging (MR750w, GE Healthcare, Waukesha, WI). After insertion of the PET detector, the final PET/MR bore is 60 cm wide (SIGNA PET/MR, GE Healthcare, Waukesha, WI). The MR performance was compared before and after the PET ring insertion. B0 homogeneity, B+1 uniformity of the body coil along with peak B+1, coherent noise, and FBIRN (Function Biomedical Informatics Research Network) tests are used to compare the MR performance. It is shown that B0 homogeneity and coherent noise have not changed according to the system specifications. Peak B+1 is increased by 33% and B+1 inhomogeneity is increased by 4% after PET ring insertion due to a smaller diameter body coil design. The FBIRN test shows similar temporal stability before and after PET ring insertion. Due to a smaller body coil on the PET/MR system, the signal fluctuation to noise ratio (SFNR) and SNR for body receive coil, are improved by ∼40% and ∼160% for Echo Planar Imaging (EPI) and spiral sequences respectively. Comparison using RF and gradient-intensive clinical sequences shows inserting the PET detectors into the wide-bore MRI has not compromised the MR image quality according to these tests.
KW - FBIRN
KW - PET/MR
KW - hybrid systems
KW - time-of-flight
UR - http://www.scopus.com/inward/record.url?scp=84982803097&partnerID=8YFLogxK
U2 - 10.1109/TNS.2016.2529624
DO - 10.1109/TNS.2016.2529624
M3 - Article
AN - SCOPUS:84982803097
SN - 0018-9499
VL - 63
SP - 2419
EP - 2423
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
IS - 5
M1 - 7473857
ER -