MR Performance Comparison of a PET/MR System Before and After SiPM-Based Time-of-Flight PET Detector Insertion

Mohammad Mehdi Khalighi, Gaspar Delso, Sri Harsha Maramraju, Timothy W. Deller, Craig S. Levin, Gary H. Glover

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A silicon photomultiplier (SiPM)-based time-of-flight capable PET detector has been integrated with a 70 cm wide-bore 3T MR scanner for simultaneous whole-body imaging (MR750w, GE Healthcare, Waukesha, WI). After insertion of the PET detector, the final PET/MR bore is 60 cm wide (SIGNA PET/MR, GE Healthcare, Waukesha, WI). The MR performance was compared before and after the PET ring insertion. B0 homogeneity, B+1 uniformity of the body coil along with peak B+1, coherent noise, and FBIRN (Function Biomedical Informatics Research Network) tests are used to compare the MR performance. It is shown that B0 homogeneity and coherent noise have not changed according to the system specifications. Peak B+1 is increased by 33% and B+1 inhomogeneity is increased by 4% after PET ring insertion due to a smaller diameter body coil design. The FBIRN test shows similar temporal stability before and after PET ring insertion. Due to a smaller body coil on the PET/MR system, the signal fluctuation to noise ratio (SFNR) and SNR for body receive coil, are improved by ∼40% and ∼160% for Echo Planar Imaging (EPI) and spiral sequences respectively. Comparison using RF and gradient-intensive clinical sequences shows inserting the PET detectors into the wide-bore MRI has not compromised the MR image quality according to these tests.

Original languageEnglish
Article number7473857
Pages (from-to)2419-2423
Number of pages5
JournalIEEE Transactions on Nuclear Science
Volume63
Issue number5
DOIs
StatePublished - Oct 2016
Externally publishedYes

Keywords

  • FBIRN
  • PET/MR
  • hybrid systems
  • time-of-flight

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