MICROSCALE IMPELLER PUMP FOR RECIRCULATING FLOW IN ORGANS-ON-CHIP AND MICROREACTORS

Sophie R. Cook, Hannah B. Musgrove, Amy L. Throckmorton, Rebecca R. Pompano

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Fluid flow is an integral part of microfluidic technology that enables these devices to generate biomimetic culture platforms to study basic tissue physiology and pathology. Unfortunately, many of the pumps that perfuse fluid at low flow rates are incompatible with use inside cell culture incubators, require many tubing connections, or are too large to run many devices at once. To address these issues, we present a user-friendly magnetically-driven impeller pump that was compatible with incubators and generated controllable low flow rates. The impeller pump was used to recirculate primary murine splenocytes, with no significant impact on cell viability.

Original languageEnglish
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1243-1244
Number of pages2
ISBN (Electronic)9781733419031
StatePublished - 2021
Externally publishedYes
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: Oct 10 2021Oct 14 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2110/14/21

Keywords

  • cell recirculation
  • DLP 3D printing
  • fluid flow
  • magnetic pump
  • microfluidics
  • Micropump

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