Medication Knowledge Graph Analysis Using the PageRank Algorithm

S. M.Shamimul Hasan, Alina Peluso, Heidi A. Hanson, Anuj J. Kapadia

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Electronic health records (EHRs) data from the US Department of Veterans Affairs (VA) show that many veterans have been treated with the Selective Serotonin Reuptake Inhibitors (SSRIs) class of antidepressant medications. It is crucial to study medications in association with other important clinical concepts to make better medication prescribing decisions and conduct better analyses of medication side effects and comorbidity. In this paper, we used PubMed's knowledge graph and PageRank algorithm to identify important concepts related to three medications that belong to the SSRI class. Our preliminary research shows that the PageRank-based publication knowledge graph analysis approach is capable of extracting interesting clinical concepts related to antidepressant medications and has the potential to improve clinical decision-making.

Original languageEnglish
Title of host publicationProceedings - 2023 IEEE 11th International Conference on Healthcare Informatics, ICHI 2023
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages495-497
Number of pages3
ISBN (Electronic)9798350302639
DOIs
StatePublished - 2023
Event11th IEEE International Conference on Healthcare Informatics, ICHI 2023 - Houston, United States
Duration: Jun 26 2023Jun 29 2023

Publication series

NameProceedings - 2023 IEEE 11th International Conference on Healthcare Informatics, ICHI 2023

Conference

Conference11th IEEE International Conference on Healthcare Informatics, ICHI 2023
Country/TerritoryUnited States
CityHouston
Period06/26/2306/29/23

Funding

This work is sponsored by the US Department of Veterans Affairs. This manuscript has been authored by UT-Battelle, LLC, under contract DE-AC05-00OR22725 with the US Department of Energy (DOE). The US government retains and the publisher, by accepting the article for publication, acknowledges that the US government retains a nonexclusive, paid-up, irrevocable, worldwide license to publish or reproduce the published form of this manuscript, or allow others to do so, for US government purposes. DOE will provide public access to these results of federally sponsored research in accordance with the DOE Public Access Plan (http://energy.gov/downloads/doe-public-access-plan).

Keywords

  • Knowledge Graph
  • PageRank
  • PubMed

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