Ligand design in lanthanide complexes for luminescence, therapy, and sensing

Patrick S. Barber, Ana de Bettencourt-Dias, Katherine R. Johnson, Jorge H.S.K. Monteiro

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

In this chapter, we explore the research done by the de Bettencourt-Dias group in luminescent lanthanide complexes. The group has isolated ligands that sensitize the luminescence of lanthanide ions, and that bear additional functional groups that impart unique properties to the resulting complexes, such as the ability to generate cytotoxic singlet oxygen, or report on, through changes in emission intensity, viscosity or temperature at the nanoscale. The energy transfer processes are accessed through one-photon excitation or two-photon excitation through the ligand, as well as upconversion. Moreover, the group explored unique coordination chemistry of lanthanides, taking advantage of secondary interactions to isolate outer-sphere complexes of these ions.

Original languageEnglish
Title of host publicationIncluding Actinides Women's Contribution to f-element Science, Part 1
EditorsJean-Claude G. Bünzli, Susan M. Kauzlarich
PublisherElsevier B.V.
Pages213-274
Number of pages62
ISBN (Print)9780443297724
DOIs
StatePublished - Jan 2024

Publication series

NameHandbook on the Physics and Chemistry of Rare Earths
Volume65
ISSN (Print)0168-1273

Keywords

  • Antenna effect
  • Carbazole
  • Complexes
  • Coordination compounds
  • Lanthanide-based luminescent therapeutics
  • Lanthanides
  • Ligand design
  • Luminescence
  • Naphthalimide
  • Nitro-benzoic acid
  • Outer-sphere complexes
  • Photocytotoxicity
  • Pybox
  • Secondary interactions
  • Sensitization
  • Singlet oxygen generation
  • Temperature sensing
  • Thiophene
  • Two-photon absorption
  • Upconversion
  • Viscosity sensing
  • Water remediation

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