Abstract
We report on the permeation of free and macrocycle-bound avobenzone across a POPC lipid bilayer through combined neutron reflectometry experiments and molecular dynamics simulations. Results indicate that the p-phosphonated calix[8]arene macrocycle limits the avobenzone penetration into the upper leaflet of the membrane. Hence, it could serve as a useful vehicle for safer formulations.
| Original language | English |
|---|---|
| Pages (from-to) | 15148-15153 |
| Number of pages | 6 |
| Journal | RSC Advances |
| Volume | 10 |
| Issue number | 26 |
| DOIs | |
| State | Published - Apr 17 2020 |
| Externally published | Yes |
Funding
This research is funded by Start-up funds (HK) and NSF grants CHE-1565632 and CHE-1955161 (TLB). FH acknowledges support from the U.S. Department of Commerce through an MSE grant (70NANB17H299). Certain commercial materials, equipment, and instruments are identified in this work to describe the experimental procedure as completely as possible. In no case does such an identification imply a recommendation or endorsement by NIST, nor does it imply that the materials, equipment, or instrument identified are necessarily the best available for the purpose. This research is funded by Start-up funds (HK) and NSF grants CHE-1565632 and CHE-1955161 (TLB). FH acknowledges support from the U.S. Department of Commerce through an MSE grant (70NANB17H299). Certain commercial materials, equipment, and instruments are identied in this work to describe the experimental procedure as completely as possible. In no case does such an identication imply a recommendation or endorsement by NIST, nor does it imply that the materials, equipment, or instrument identied are necessarily the best available for the purpose.
| Funders | Funder number |
|---|---|
| National Science Foundation | CHE-1955161, CHE-1565632, 1955161 |
| National Institute of Standards and Technology | |
| U.S. Department of Commerce | |
| David O. McKay School of Education, Brigham Young University | 70NANB17H299 |