In situ molecular imaging of a hydrated biofilm in a microfluidic reactor by ToF-SIMS

Xin Hua, Xiao Ying Yu, Zhaoying Wang, Li Yang, Bingwen Liu, Zihua Zhu, Abigail E. Tucker, William B. Chrisler, Eric A. Hill, Theva Thevuthasan, Yuehe Lin, Songqin Liu, Matthew J. Marshall

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

A novel microfluidic reactor for biofilm growth and in situ characterization using time-of-flight secondary ion mass spectrometry (ToF-SIMS) was constructed to enable two-dimensional chemical imaging of hydrated biofilms. We demonstrate the detection of characteristic fatty acid fragments from microfluidic reactor-grown biofilms and illustrate advantages of hydrated-state ToF-SIMS imaging.

Original languageEnglish
Pages (from-to)1609-1613
Number of pages5
JournalAnalyst
Volume139
Issue number7
DOIs
StatePublished - Mar 3 2014
Externally publishedYes

Funding

FundersFunder number
U.S. Department of EnergyDE-AC05-76RL01830

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