In situ formation of gold-"decorated" vesicles from a RAFT-synthesized, thermally responsive block copolymer

Yuting Li; Adam E. Smith; Brad S. Lokitz; Charles L. McCormick

doi:10.1021/ma071488s

In situ formation of gold-"decorated" vesicles from a RAFT-synthesized, thermally responsive block copolymer

Yuting Li, Adam E. Smith, Brad S. Lokitz, Charles L. McCormick

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Abstract

Thermally responsive vesicle system decorated with gold nanoparticles have been prepared from the self-assembly of a thermally responsive poly[2-(dimethylamino)ethyl methacrylate-block-(N-isopropylacrylamide)] (PDMAEMA-b-PNIPAM) block copolymer. Simply mixing the vesicle solution with a solution of NaAuCl ₄ without any external reducing agent leads to the formation of gold nanoparticle decorated vesicles. The conversion of complexed AuCl ₄ to zero-valent gold nanoparticles was conformed by the observation of surface plasmon resonance. Reversible addition-fragmentation chain-transfer (RAFT) polymerization was used for the synthesis of the diblock copolymer composed of pH-responsive DMAEMA and the thermally responsive NIPAM segments. DLS, NMR spectra, and TEM were used in the course of various steps of the reaction.

Original language	English
Pages (from-to)	8524-8526
Number of pages	3
Journal	Macromolecules
Volume	40
Issue number	24
DOIs	https://doi.org/10.1021/ma071488s
State	Published - Nov 27 2007
Externally published	Yes

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title = "In situ formation of gold-{"}decorated{"} vesicles from a RAFT-synthesized, thermally responsive block copolymer",

abstract = "Thermally responsive vesicle system decorated with gold nanoparticles have been prepared from the self-assembly of a thermally responsive poly[2-(dimethylamino)ethyl methacrylate-block-(N-isopropylacrylamide)] (PDMAEMA-b-PNIPAM) block copolymer. Simply mixing the vesicle solution with a solution of NaAuCl 4 without any external reducing agent leads to the formation of gold nanoparticle decorated vesicles. The conversion of complexed AuCl 4 to zero-valent gold nanoparticles was conformed by the observation of surface plasmon resonance. Reversible addition-fragmentation chain-transfer (RAFT) polymerization was used for the synthesis of the diblock copolymer composed of pH-responsive DMAEMA and the thermally responsive NIPAM segments. DLS, NMR spectra, and TEM were used in the course of various steps of the reaction.",

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AU - Li, Yuting

AU - Smith, Adam E.

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AU - McCormick, Charles L.

PY - 2007/11/27

Y1 - 2007/11/27

N2 - Thermally responsive vesicle system decorated with gold nanoparticles have been prepared from the self-assembly of a thermally responsive poly[2-(dimethylamino)ethyl methacrylate-block-(N-isopropylacrylamide)] (PDMAEMA-b-PNIPAM) block copolymer. Simply mixing the vesicle solution with a solution of NaAuCl 4 without any external reducing agent leads to the formation of gold nanoparticle decorated vesicles. The conversion of complexed AuCl 4 to zero-valent gold nanoparticles was conformed by the observation of surface plasmon resonance. Reversible addition-fragmentation chain-transfer (RAFT) polymerization was used for the synthesis of the diblock copolymer composed of pH-responsive DMAEMA and the thermally responsive NIPAM segments. DLS, NMR spectra, and TEM were used in the course of various steps of the reaction.

AB - Thermally responsive vesicle system decorated with gold nanoparticles have been prepared from the self-assembly of a thermally responsive poly[2-(dimethylamino)ethyl methacrylate-block-(N-isopropylacrylamide)] (PDMAEMA-b-PNIPAM) block copolymer. Simply mixing the vesicle solution with a solution of NaAuCl 4 without any external reducing agent leads to the formation of gold nanoparticle decorated vesicles. The conversion of complexed AuCl 4 to zero-valent gold nanoparticles was conformed by the observation of surface plasmon resonance. Reversible addition-fragmentation chain-transfer (RAFT) polymerization was used for the synthesis of the diblock copolymer composed of pH-responsive DMAEMA and the thermally responsive NIPAM segments. DLS, NMR spectra, and TEM were used in the course of various steps of the reaction.

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In situ formation of gold-"decorated" vesicles from a RAFT-synthesized, thermally responsive block copolymer

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