Improving tissue segmentation of human brain MRI through preprocessing by the Gegenbauer reconstruction method

Rick Archibald, Kewei Chen, Anne Gelb, Rosemary Renaut

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

The Gegenbauer image reconstruction method, previously shown to improve the quality of magnetic resonance images, is utilized in this study as a segmentation preprocessing step. It is demonstrated that, for all simulated and real magnetic resonance images used in this study, the Gegenbauer reconstruction method improves the accuracy of segmentation. Although it is more desirable to use the k-space data for the Gegenbauer reconstruction method, only information acquired from MR images is necessary for the reconstruction, making the procedure completely self-contained and viable for all human brain segmentation algorithms.

Original languageEnglish
Pages (from-to)489-502
Number of pages14
JournalNeuroImage
Volume20
Issue number1
DOIs
StatePublished - Sep 1 2003
Externally publishedYes

Funding

The authors of this work were supported in part by the Arizona Center for Alzheimer’s Disease Research (R. Archibald, K. Chen, A. Gelb, and R. Renaut), the Center for System Science and Engineering Research at Arizona State University (R. Archibald and A. Gelb), the Department of Mathematics and Statistics at Arizona State University (R. Archibald, K. Chen, A. Gelb, and R. Renaut), the John von Neumann visiting Professorship of the Zentrum Mathematik, Technische Universitaet Muenchen (R. Renaut), NSF Grant DMS 9977234 (R. Renaut), and NSF Grant DMS 01-07428 (A. Gelb).

FundersFunder number
Arizona Center for Alzheimer’s Disease Research
Center for System Science and Engineering Research at Arizona State University
Zentrum Mathematik
National Science FoundationDMS 01-07428, DMS 9977234
Technische Universität München

    Keywords

    • Brain extraction
    • Edge detection
    • Gegenbauer reconstruction
    • Noise
    • Segmentation

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