Improved Biomass Production and Secondary Metabolism: A Critical Review of Grafting in Cannabis sativa

  • S. M. Ahsan
  • , Md Injamum-Ul-Hoque
  • , Md Mezanur Rahman
  • , Sang Mo Kang
  • , In Jung Lee
  • , Hyong Woo Choi

Research output: Contribution to journalReview articlepeer-review

Abstract

Cannabis sativa L. is a versatile plant with applications in various sectors such as agriculture, medicine, food, and cosmetics. The therapeutic properties of cannabis are often linked to its secondary compounds. The worldwide cannabis market is undergoing swift changes due to varying legal frameworks. Medicinal cannabis (as a heterozygous and dioecious species) is distinct from most annual crops grown in controlled environments, typically propagated through stem cutting rather than seeds to ensure genetic uniformity. Consequently, as with any commercially cultivated crop, biomass yield plays a crucial role in overall productivity. The key factors involved in cultivation conditions, such as successful root establishment, stress tolerance, and the production cycle duration, are critical for safeguarding, improving, and optimizing plant yield. Grafting is a long-established horticultural practice that mechanically joins the scion and rootstock of distinct genetic origins by merging their vascular systems. This approach can mitigate undesirable traits by leveraging the strengths of particular plants, proving beneficial to various applications. Grafting is not used commercially in Cannabis. Only three very recent investigations suggest that grafting holds significant promise for enhancing both the agronomic and medicinal potential of Cannabis. This review critically examines the latest advancements in cannabis grafting and explores prospects for improving biomass (stem, root, flower, etc.) yield and secondary metabolite production.

Original languageEnglish
Article number2347
JournalPlants
Volume14
Issue number15
DOIs
StatePublished - Aug 2025
Externally publishedYes

Keywords

  • cannabis
  • oxidative stress
  • phytohormones
  • secondary metabolites
  • vascular tissue

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