High-resolution X-ray CT screening of mutant mouse models

M. J. Paulus; S. S. Gleason; H. Sari-Sarraf; D. K. Johnson; C. J. Foltz; D. W. Austin; M. E. Easterly; E. J. Michaud; M. S. Dhar; P. R. Hunsicker; J. W. Wall; M. Schell

High-resolution X-ray CT screening of mutant mouse models

M. J. Paulus, S. S. Gleason, H. Sari-Sarraf, D. K. Johnson, C. J. Foltz, D. W. Austin, M. E. Easterly, E. J. Michaud, M. S. Dhar, P. R. Hunsicker, J. W. Wall, M. Schell

Oak Ridge National Laboratory

Research output: Contribution to journal › Conference article › peer-review

20 Scopus citations

Abstract

A dedicated small animal x-ray computed tomography system has been developed to screen mutagenized mice for anatomical phenotypes. The key components of the data acquisition instrumentation are described along with the system performance parameters. Image reconstruction, visualization and segmentation software algorithms are described. Two contrast media regimens are described and representative studies of mice with adipose, soft and skeletal tissue abnormalities are presented.

Original language	English
Pages (from-to)	270-279
Number of pages	10
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3921
State	Published - 2000
Event	Optical Diagnostics of Living Cells III - San Jose, CA, USA Duration: Jan 24 2000 → Jan 25 2000

Cite this

@article{bce2d95570fb418985ae799ea2342873,

title = "High-resolution X-ray CT screening of mutant mouse models",

abstract = "A dedicated small animal x-ray computed tomography system has been developed to screen mutagenized mice for anatomical phenotypes. The key components of the data acquisition instrumentation are described along with the system performance parameters. Image reconstruction, visualization and segmentation software algorithms are described. Two contrast media regimens are described and representative studies of mice with adipose, soft and skeletal tissue abnormalities are presented.",

author = "Paulus, {M. J.} and Gleason, {S. S.} and H. Sari-Sarraf and Johnson, {D. K.} and Foltz, {C. J.} and Austin, {D. W.} and Easterly, {M. E.} and Michaud, {E. J.} and Dhar, {M. S.} and Hunsicker, {P. R.} and Wall, {J. W.} and M. Schell",

year = "2000",

language = "English",

volume = "3921",

pages = "270--279",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "Society of Photo-Optical Instrumentation Engineers",

note = "Optical Diagnostics of Living Cells III ; Conference date: 24-01-2000 Through 25-01-2000",

}

TY - JOUR

T1 - High-resolution X-ray CT screening of mutant mouse models

AU - Paulus, M. J.

AU - Gleason, S. S.

AU - Sari-Sarraf, H.

AU - Johnson, D. K.

AU - Foltz, C. J.

AU - Austin, D. W.

AU - Easterly, M. E.

AU - Michaud, E. J.

AU - Dhar, M. S.

AU - Hunsicker, P. R.

AU - Wall, J. W.

AU - Schell, M.

PY - 2000

Y1 - 2000

N2 - A dedicated small animal x-ray computed tomography system has been developed to screen mutagenized mice for anatomical phenotypes. The key components of the data acquisition instrumentation are described along with the system performance parameters. Image reconstruction, visualization and segmentation software algorithms are described. Two contrast media regimens are described and representative studies of mice with adipose, soft and skeletal tissue abnormalities are presented.

AB - A dedicated small animal x-ray computed tomography system has been developed to screen mutagenized mice for anatomical phenotypes. The key components of the data acquisition instrumentation are described along with the system performance parameters. Image reconstruction, visualization and segmentation software algorithms are described. Two contrast media regimens are described and representative studies of mice with adipose, soft and skeletal tissue abnormalities are presented.

UR - http://www.scopus.com/inward/record.url?scp=0033730957&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0033730957

SN - 0277-786X

VL - 3921

SP - 270

EP - 279

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Optical Diagnostics of Living Cells III

Y2 - 24 January 2000 through 25 January 2000

ER -

High-resolution X-ray CT screening of mutant mouse models

Abstract

Other files and links

Fingerprint

Cite this