Graphene field effect transistors for highly sensitive and selective detection of K+ ions

Hongmei Li; Yihao Zhu; Md Sayful Islam; Md Anisur Rahman; Kenneth B. Walsh; Goutam Koley

doi:10.1016/j.snb.2017.06.129

Graphene field effect transistors for highly sensitive and selective detection of K⁺ ions

Hongmei Li, Yihao Zhu, Md Sayful Islam, Md Anisur Rahman, Kenneth B. Walsh, Goutam Koley

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

Graphene-based ion sensitive field effect transistors (GISFETs) with high sensitivity and selectivity for K⁺ ion detection have been demonstrated utilizing valinomycin based ion selective membrane. The performance of the GISFETs for K⁺ ion detection was studied in various media over a concentration range of 1 μM–2 mM. The sensitivity of the sensor was found to be >60 mV/decade, which is comparable to the best Si-based commercial ISFETs, with negligible interference found from Na⁺ and Ca²⁺ ions in high concentration. The sensor performance did not change significantly in Tris–HCl solution or with repeated testing over a period of two months highlighting its reliability and effectiveness for physiological monitoring. The performance of the sensor also remained unchanged when fabricated on biocompatible polyethylene terephthalate (PET) substrate, showing significant potential for developing flexible bio-implantable graphene-based ISFETs.

Original language	English
Pages (from-to)	759-765
Number of pages	7
Journal	Sensors and Actuators, B: Chemical
Volume	253
DOIs	https://doi.org/10.1016/j.snb.2017.06.129
State	Published - 2017
Externally published	Yes

Funding

We would like to thank Chuanbing Tang group at the University of South Carolina for performing the synthesizing of the polymer matrix in this research. Financial support for this work from the National Science Foundation (Grants Nos. IIP-1512342, CBET-1606882, and IIP-1602006) is also thankfully acknowledged.

Funders	Funder number
National Science Foundation	IIP-1602006, IIP-1512342, CBET-1606882

Keywords

Graphene
Ion selective membrane
Ion sensitive field effect transistor
K ion detection

Access to Document

10.1016/j.snb.2017.06.129

Cite this

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title = "Graphene field effect transistors for highly sensitive and selective detection of K+ ions",

abstract = "Graphene-based ion sensitive field effect transistors (GISFETs) with high sensitivity and selectivity for K+ ion detection have been demonstrated utilizing valinomycin based ion selective membrane. The performance of the GISFETs for K+ ion detection was studied in various media over a concentration range of 1 μM–2 mM. The sensitivity of the sensor was found to be >60 mV/decade, which is comparable to the best Si-based commercial ISFETs, with negligible interference found from Na+ and Ca2+ ions in high concentration. The sensor performance did not change significantly in Tris–HCl solution or with repeated testing over a period of two months highlighting its reliability and effectiveness for physiological monitoring. The performance of the sensor also remained unchanged when fabricated on biocompatible polyethylene terephthalate (PET) substrate, showing significant potential for developing flexible bio-implantable graphene-based ISFETs.",

keywords = "Graphene, Ion selective membrane, Ion sensitive field effect transistor, K ion detection",

author = "Hongmei Li and Yihao Zhu and Islam, {Md Sayful} and Rahman, {Md Anisur} and Walsh, {Kenneth B.} and Goutam Koley",

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AU - Li, Hongmei

AU - Zhu, Yihao

AU - Islam, Md Sayful

AU - Rahman, Md Anisur

AU - Walsh, Kenneth B.

AU - Koley, Goutam

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AB - Graphene-based ion sensitive field effect transistors (GISFETs) with high sensitivity and selectivity for K+ ion detection have been demonstrated utilizing valinomycin based ion selective membrane. The performance of the GISFETs for K+ ion detection was studied in various media over a concentration range of 1 μM–2 mM. The sensitivity of the sensor was found to be >60 mV/decade, which is comparable to the best Si-based commercial ISFETs, with negligible interference found from Na+ and Ca2+ ions in high concentration. The sensor performance did not change significantly in Tris–HCl solution or with repeated testing over a period of two months highlighting its reliability and effectiveness for physiological monitoring. The performance of the sensor also remained unchanged when fabricated on biocompatible polyethylene terephthalate (PET) substrate, showing significant potential for developing flexible bio-implantable graphene-based ISFETs.

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