Abstract
We sequenced sarbecovirus from Rhinolophus spp. bats in Bandarban District, Bangladesh, in a genomic surveillance campaign during 2022-2023. Sequences shared identity with SARS-CoV-1 Tor2, which caused an outbreak of human illnesses in 2003. Describing the genetic diversity and zoonotic potential of reservoir pathogens can aid in identifying sources of future spillovers.
| Original language | English |
|---|---|
| Pages (from-to) | 1652-1656 |
| Number of pages | 5 |
| Journal | Emerging Infectious Diseases |
| Volume | 31 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2025 |
Funding
We thank April Manzella for Biosafety Level 4 laboratory support, Mike Lee for bioinformatics support, and Robert Bull for support and encouragement throughout this study. We also thank Emma Spence, Sara LaTrielle, Manuel Ruiz-Aravena, Agnieszka Rynda-Apple, and Monica Hall for administrative and logistic support. C.M., R.K.P., and E.S.G. were supported by the Defense Advanced Research Projects Agency’s PREventing EMerging Pathogenic Threats program (cooperative agreement no. D18AC00031). R.K.P. (grant no. DEB1716698) and J.L., D.J., and R.K.P. (grant nos. EF-2133763 and EF-2231624) were supported by the National Science Foundation. This work was funded in part under agreement no. HSHQDC-15-C-00064 awarded to Battelle National Biodefense Institute by the US Department of Homeland Security (DHS) Science and Technology Directorate for the management and operation of the National Biodefense Analysis and Countermeasures Center, a federally funded research and development center.