Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh

Christopher Bradburne; Ausraful Islam; Ian Bird; Elliott Abbott; Sarah Harrison; Morgan Chunn; Diana Radune; Md Rakib Hasan; Brian Janes; Sean Lovett; John Lagergren; Timothy O’Hanlon; Konad Debnath; Clifton McKee; Mohammad Enayet Hossain; Molly Gallagher; Daniel Jacobson; Mohammed Ziaur Rahman; Katie Caviness; Raina K. Plowright; Emily S. Gurley

doi:10.3201/eid3108.250071

Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh

Christopher Bradburne
, Ausraful Islam
, Ian Bird
, Elliott Abbott
, Sarah Harrison
, Morgan Chunn
, Diana Radune
, Md Rakib Hasan
, Brian Janes
, Sean Lovett
, John Lagergren
, Timothy O’Hanlon
, Konad Debnath
, Clifton McKee
, Mohammad Enayet Hossain
, Molly Gallagher
, Daniel Jacobson
, Mohammed Ziaur Rahman
, Katie Caviness
, Raina K. Plowright

Emily S. Gurley

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We sequenced sarbecovirus from Rhinolophus spp. bats in Bandarban District, Bangladesh, in a genomic surveillance campaign during 2022-2023. Sequences shared identity with SARS-CoV-1 Tor2, which caused an outbreak of human illnesses in 2003. Describing the genetic diversity and zoonotic potential of reservoir pathogens can aid in identifying sources of future spillovers.

Original language	English
Pages (from-to)	1652-1656
Number of pages	5
Journal	Emerging Infectious Diseases
Volume	31
Issue number	8
DOIs	https://doi.org/10.3201/eid3108.250071
State	Published - Aug 2025

Funding

This manuscript has been coauthored by UT-Battelle, LLC, under contract no. DE-AC05-00OR22725 with the US Department of Energy (DOE). The publisher, by accepting the article for publication, acknowledges that the US government retains a nonexclusive, paid-up, irrevocable, worldwide license to publish or reproduce the published form of this manuscript, or allow others to do so, for US government purposes. DOE will provide public access to these results of federally sponsored research in accordance with the DOE Public Access Plan (http://energy.gov/downloads/doe-public-access-plan). We thank April Manzella for Biosafety Level 4 laboratory support, Mike Lee for bioinformatics support, and Robert Bull for support and encouragement throughout this study. We also thank Emma Spence, Sara LaTrielle, Manuel Ruiz-Aravena, Agnieszka Rynda-Apple, and Monica Hall for administrative and logistic support. C.M., R.K.P., and E.S.G. were supported by the Defense Advanced Research Projects Agency’s PREventing EMerging Pathogenic Threats program (cooperative agreement no. D18AC00031). R.K.P. (grant no. DEB1716698) and J.L., D.J., and R.K.P. (grant nos. EF-2133763 and EF-2231624) were supported by the National Science Foundation. This work was funded in part under agreement no. HSHQDC-15-C-00064 awarded to Battelle National Biodefense Institute by the US Department of Homeland Security (DHS) Science and Technology Directorate for the management and operation of the National Biodefense Analysis and Countermeasures Center, a federally funded research and development center. C.M., R.K.P., and E.S.G. were supported by the Defense Advanced Research Projects Agency’s PREventing EMerging Pathogenic Threats program (cooperative agreement no. D18AC00031). R.K.P. (grant no. DEB-1716698) and J.L., D.J., and R.K.P. (grant nos. EF-2133763 and EF-2231624) were supported by the National Science Foundation. This work was funded in part under agreement no. HSHQDC-15-C-00064 awarded to Battelle National Biodefense Institute by the US Department of Homeland Security (DHS) Science and Technology Directorate for the management and operation of the National Biodefense Analysis and Countermeasures Center, a federally funded research and development center.

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10.3201/eid3108.250071

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Bradburne, C., Islam, A., Bird, I., Abbott, E., Harrison, S., Chunn, M., Radune, D., Hasan, M. R., Janes, B., Lovett, S., Lagergren, J., O’Hanlon, T., Debnath, K., McKee, C., Hossain, M. E., Gallagher, M., Jacobson, D., Rahman, M. Z., Caviness, K., ... Gurley, E. S. (2025). Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh. Emerging Infectious Diseases, 31(8), 1652-1656. https://doi.org/10.3201/eid3108.250071

@article{46d696d7d9464fafb061159c6a6a5f5c,

title = "Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh",

abstract = "We sequenced sarbecovirus from Rhinolophus spp. bats in Bandarban District, Bangladesh, in a genomic surveillance campaign during 2022-2023. Sequences shared identity with SARS-CoV-1 Tor2, which caused an outbreak of human illnesses in 2003. Describing the genetic diversity and zoonotic potential of reservoir pathogens can aid in identifying sources of future spillovers.",

author = "Christopher Bradburne and Ausraful Islam and Ian Bird and Elliott Abbott and Sarah Harrison and Morgan Chunn and Diana Radune and Hasan, \{Md Rakib\} and Brian Janes and Sean Lovett and John Lagergren and Timothy O{\textquoteright}Hanlon and Konad Debnath and Clifton McKee and Hossain, \{Mohammad Enayet\} and Molly Gallagher and Daniel Jacobson and Rahman, \{Mohammed Ziaur\} and Katie Caviness and Plowright, \{Raina K.\} and Gurley, \{Emily S.\}",

year = "2025",

month = aug,

doi = "10.3201/eid3108.250071",

language = "English",

volume = "31",

pages = "1652--1656",

journal = "Emerging Infectious Diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention",

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}

Bradburne, C, Islam, A, Bird, I, Abbott, E, Harrison, S, Chunn, M, Radune, D, Hasan, MR, Janes, B, Lovett, S, Lagergren, J, O’Hanlon, T, Debnath, K, McKee, C, Hossain, ME, Gallagher, M, Jacobson, D, Rahman, MZ, Caviness, K, Plowright, RK & Gurley, ES 2025, 'Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh', Emerging Infectious Diseases, vol. 31, no. 8, pp. 1652-1656. https://doi.org/10.3201/eid3108.250071

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T1 - Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh

AU - Bradburne, Christopher

AU - Islam, Ausraful

AU - Bird, Ian

AU - Abbott, Elliott

AU - Harrison, Sarah

AU - Chunn, Morgan

AU - Radune, Diana

AU - Hasan, Md Rakib

AU - Janes, Brian

AU - Lovett, Sean

AU - Lagergren, John

AU - O’Hanlon, Timothy

AU - Debnath, Konad

AU - McKee, Clifton

AU - Hossain, Mohammad Enayet

AU - Gallagher, Molly

AU - Jacobson, Daniel

AU - Rahman, Mohammed Ziaur

AU - Caviness, Katie

AU - Plowright, Raina K.

AU - Gurley, Emily S.

PY - 2025/8

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N2 - We sequenced sarbecovirus from Rhinolophus spp. bats in Bandarban District, Bangladesh, in a genomic surveillance campaign during 2022-2023. Sequences shared identity with SARS-CoV-1 Tor2, which caused an outbreak of human illnesses in 2003. Describing the genetic diversity and zoonotic potential of reservoir pathogens can aid in identifying sources of future spillovers.

AB - We sequenced sarbecovirus from Rhinolophus spp. bats in Bandarban District, Bangladesh, in a genomic surveillance campaign during 2022-2023. Sequences shared identity with SARS-CoV-1 Tor2, which caused an outbreak of human illnesses in 2003. Describing the genetic diversity and zoonotic potential of reservoir pathogens can aid in identifying sources of future spillovers.

UR - https://www.scopus.com/pages/publications/105012317696

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SN - 1080-6040

VL - 31

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JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 8

ER -

Genomic Surveillance Detection of SARS-CoV-1-Like Viruses in Rhinolophidae Bats, Bandarban Region, Bangladesh

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