Abstract
Bench-scale reactors were operated in continuous recycle and single-pass modes using immobilized porcine lipase to catalyze gas-phase esterification of ethyl alcohol with two carboxylic acids (acetic acid and propionic acid). Approximately one order of magnitude increases (over uncatalyzed reactions) in conversion were achieved; production concentrations ranged from 0.1 to 0.5 mM in air, and were affected strongly by substrate concentration and acid-induced enzyme inactivation.
| Original language | English |
|---|---|
| Pages (from-to) | 747-750 |
| Number of pages | 4 |
| Journal | Biotechnology Techniques |
| Volume | 11 |
| Issue number | 10 |
| DOIs | |
| State | Published - 1997 |
Funding
The material presented in this manuscript resulted from efforts sponsored by the Advanced Industrial Concepts Division – Biological and Chemical Technologies Research (BTCR) Program – US Department of Energy, under contract with Lockheed Martin Energy Research Corporation. The authors would like to thank C. Chris Gable (ORNL) for technical support.