Fundamentals of bio-electrochemical sensing

Mahesh M. Shanbhag, G. Manasa, Ronald J. Mascarenhas, Kunal Mondal, Nagaraj P. Shetti

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

The utilization of bio-functionalities such as biorecognition or catalysis derived them their name biosensors. Bio-electrochemical sensing is a new discipline that combines the advantages of biological detection and electrochemical transduction. Bio-electrochemical sensors are devices that use biological materials such as enzymes, antibodies, DNA, or cells as receptors to detect target analytes in a variety of samples. Electrodes convert biological interactions into electrical impulses, which can be studied using various electrochemical techniques. Bio-electrochemical sensors have demonstrated significant promise for use in clinical diagnostics, environmental monitoring, food safety, and biotechnology. Biosensors have received numerous applications in recent years because they are fast, simple, and inexpensive for practical applications. In this article, we cover the basic principles, design strategies, immobilization and regeneration techniques, along with the advantages and applications of bio-electrochemical sensors. Finally, this article discusses the rationale for developing electrochemical biosensors in the context of the various bio-receptors that can be applied.

Original languageEnglish
Article number100516
JournalChemical Engineering Journal Advances
Volume16
DOIs
StatePublished - Nov 15 2023

Funding

Kunal Mondal gratefully acknowledges the Department of Energy and Environment Science and Technology at the Idaho National Laboratory, USA for their support. Kunal Mondal also wants to thank Oak Ridge National Laboratory, USA, for their support.

FundersFunder number
Department of Energy and Environment Science and Technology
Oak Ridge National Laboratory
Idaho National Laboratory

    Keywords

    • Bio-receptors
    • Biosensors
    • Electrochemical transducer
    • Electrochemistry
    • Voltammetry

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