Abstract
Biomineralization processes identified within diatoms have inspired the design of synthetic silica structures in vitro using alkoxysilane precursors. Here we explore the use of the machinery within the living diatom to fabricate organo-silica constructs using a combination of alkoxysilane and organoalkoxysilane precursors. We report on the incorporation of thiol moieties into the diatom during frustule synthesis. Formation of valves within the parent diatom is monitored using fluorescence microscopy, and the modification of the chemical composition of the diatom is confirmed using energy dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy and 29 Si-nuclear magnetic resonance spectroscopy. Chemical modification is achieved without loss of the nano-scale architectural features of the frustule. Extension of this work may allow the chemistry of the diatom to be tailored during synthesis.
| Original language | English |
|---|---|
| Article number | 3683 |
| Journal | Nature Communications |
| Volume | 4 |
| DOIs | |
| State | Published - 2013 |
| Externally published | Yes |
Funding
This material is based on works supported by Science Foundation Ireland under Grant No. [07/SRC/B1163] and MINECO (MAT2009-10214 and MAT2012-34811). The AFM equipment used for this work was funded by Science Foundation Ireland (grant No. 07/IN1/B031). We thank Dr Éadaoin Timmins, Mr Pierce Lalor and Mr David Connolly at National University of Ireland, Galway, for assistance with SEM, TEM and fluorescence microscopy imaging. We would like to thank Mr Daniel Kerr, Mr Ambrose O’Halloran, Mr Rafael Salas and Dr Oliver Carroll for additional technical assistance.