Fractal texture analysis of perfusion lung scans

Georgia D. Tourassi, Erik D. Frederick, Neal F. Vittitoe, R. Edward Coleman

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The purpose of this study is to investigate if fractal texture analysis can assist in the diagnostic interpretation of perfusion lung scans. Forty- five perfusion scans were acquired from patients with clinical suspicion of acute pulmonary embolism (PE) who underwent pulmonary angiography for final diagnosis. Fractal texture analysis was performed on 270 regions of interest (ROIs) extracted from the posterior view of the lung scans. Specifically, there were 94 normally perfused ROIs and 176 abnormal ROIs representing various lung diseases including PE and obstructive pulmonary disease (OPD). The average fractal dimension (FD) of normal ROIs was statistically significantly higher than that of abnormal ROTs. Furthermore, the FDs of abnormal ROTs with PE were significantly lower than the FDs of ROIs with OPD present. (C) 2000 Academic Press.

Original languageEnglish
Pages (from-to)161-171
Number of pages11
JournalComputers and Biomedical Research
Volume33
Issue number3
DOIs
StatePublished - Jun 2000
Externally publishedYes

Funding

1This work was supported in part by Grant R29-HL-52826 from the National Heart, Lung, and Blood Institute and by Grant RG 98-0324 from the Whitaker Foundation. 2To whom correspondence should be addressed at Duke University Medical Center, Box 3302, Durham, NC 27710. Fax: 919-684-7122. E-mail: [email protected]. 161

FundersFunder number
National Heart, Lung, and Blood InstituteRG 98-0324, R29HL052826
Whitaker Foundation

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