Exciting Green Flourescent Protein

Volkhard Helms; Erik F.Y. Hom; T. P. Straatsma; J. Andrew McCammon; Peter Langhoff

doi:10.1021/bk-1998-0712.ch019

Exciting Green Flourescent Protein

Volkhard Helms, Erik F.Y. Hom, T. P. Straatsma, J. Andrew McCammon, Peter Langhoff

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Dynamical and luminescent properties of the Green Fluorescent Protein (GFP) are being explored via molecular dynamics (MD) simulations and quantum chemistry calculations with the aim of facilitating the rational development of GFP as a probe for cellular functions. Results from an MD simulation of wild type GFP demonstrate the rigidity of the structural framework of GFP, and a very stable hydrogen bond network around the chromophore. Furthermore, excited state calculations have been performed on the chromophore in vacuum, and we report about our work in progress here.

Original language	English
Pages (from-to)	288-295
Number of pages	8
Journal	ACS Symposium Series
Volume	712
DOIs	https://doi.org/10.1021/bk-1998-0712.ch019
State	Published - 1998
Externally published	Yes

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title = "Exciting Green Flourescent Protein",

abstract = "Dynamical and luminescent properties of the Green Fluorescent Protein (GFP) are being explored via molecular dynamics (MD) simulations and quantum chemistry calculations with the aim of facilitating the rational development of GFP as a probe for cellular functions. Results from an MD simulation of wild type GFP demonstrate the rigidity of the structural framework of GFP, and a very stable hydrogen bond network around the chromophore. Furthermore, excited state calculations have been performed on the chromophore in vacuum, and we report about our work in progress here.",

author = "Volkhard Helms and Hom, {Erik F.Y.} and Straatsma, {T. P.} and McCammon, {J. Andrew} and Peter Langhoff",

year = "1998",

doi = "10.1021/bk-1998-0712.ch019",

language = "English",

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journal = "ACS Symposium Series",

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AU - Helms, Volkhard

AU - Hom, Erik F.Y.

AU - Straatsma, T. P.

AU - McCammon, J. Andrew

AU - Langhoff, Peter

PY - 1998

Y1 - 1998

N2 - Dynamical and luminescent properties of the Green Fluorescent Protein (GFP) are being explored via molecular dynamics (MD) simulations and quantum chemistry calculations with the aim of facilitating the rational development of GFP as a probe for cellular functions. Results from an MD simulation of wild type GFP demonstrate the rigidity of the structural framework of GFP, and a very stable hydrogen bond network around the chromophore. Furthermore, excited state calculations have been performed on the chromophore in vacuum, and we report about our work in progress here.

AB - Dynamical and luminescent properties of the Green Fluorescent Protein (GFP) are being explored via molecular dynamics (MD) simulations and quantum chemistry calculations with the aim of facilitating the rational development of GFP as a probe for cellular functions. Results from an MD simulation of wild type GFP demonstrate the rigidity of the structural framework of GFP, and a very stable hydrogen bond network around the chromophore. Furthermore, excited state calculations have been performed on the chromophore in vacuum, and we report about our work in progress here.

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U2 - 10.1021/bk-1998-0712.ch019

DO - 10.1021/bk-1998-0712.ch019

M3 - Article

AN - SCOPUS:0042354349

SN - 0097-6156

VL - 712

SP - 288

EP - 295

JO - ACS Symposium Series

JF - ACS Symposium Series

ER -

Exciting Green Flourescent Protein

Abstract

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