Abstract
Enriched tungsten disulfide (186WS2) was evaluated at increasing proton beam currents (20-50 μA) and times (up to 4 h) on a GE PETtrace cyclotron for production of high specific activity (HSA) 186Re. The HSA 186Re was separated from the irradiated target as [186Re][ReO4]- by a liquid-liquid extraction method and radiolabeled with a new N2S2 ligand (222-MAMA-N-ethylpropionate). The enriched 186W was recovered from the extraction process, analyzed for purity and enrichment, and converted back to the disulfide (186WS2). The results demonstrate that the 186WS2 is an easily pressed target material that can withstand relatively high currents and can be readily recovered and recycled. The 186Re produced was isolated in high specific activity and readily formed the radiotracers [186Re][ReO(222-MAMA-N-ethylpropionate)] and [186Re][Re(CO)3(OH2)3] +.
Original language | English |
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Pages (from-to) | 739-749 |
Number of pages | 11 |
Journal | Radiochimica Acta |
Volume | 110 |
Issue number | 6-9 |
DOIs | |
State | Published - Jun 1 2022 |
Externally published | Yes |
Keywords
- W(p,n)Re
- high specific activity (HSA) Re
- NSligand (222-MAMA-N-ethylpropionate)
- ReO(222-MAMA-N-ethylpropionate)
- tungsten disulfide (WS)