Erratum: Chelating Rare-Earth Metals (Ln³⁺) And ²²⁵Ac³⁺ With The Dual-Size-Selective Macrocyclic Ligand Py₂‑Macrodipa (Inorganic Chemistry (2022) 61:32 (12847-12855) DOI: 10.1021/acs.inorgchem.2c01998)

Page 12852 and 12853. In Figure 5 of the paper and Table S3 of the Supporting Information, the radiochemical yields (RCYs) from the complexation of ²²⁵Ac by DOTA at 25 °C were reported incorrectly as <5% across the entire range of chelator concentrations investigated (10⁻³−10⁻⁸ M). Subsequent experiments revealed that the iTLC-silica gel (iTLC-SG, Agilent) method employed to analyze the radiolabeling reactions is ineffective at separating DOTA-complexed ²²⁵Ac from uncomplexed ²²⁵Ac, regardless of whether a mobile phase of EDTA (0.05 M, pH 6) or sodium citrate (0.4 M, pH 4, with 10% MeOH) is used. Separation of the ²²⁵Ac−DOTA complex from free ²²⁵Ac can instead be achieved using aluminum-backed silica TLC plates (TLC-SG, silica gel 60, F₂₅₄, Merck) in conjunction with a mobile phase of sodium citrate (0.4 M, pH 4) containing 10% MeOH. Under these conditions, the ²²⁵Ac−DOTA complex remains at the baseline (R_f = 0) and free ²²⁵Ac migrates with the solvent front (R_f = 1). Using this chromatographic separation system, the RCYs for ²²⁵Ac radiolabeling of DOTA were determined to be above 10% at chelator concentrations of 10⁻³ and 10⁻⁴ M. The corrected RCYs at both the 5 and 60 min reaction times are provided in the revised Figure 5 and Table S3 below. These corrections do not affect the conclusions presented in the published paper. (Table Presented).