Electromechanical imaging of biological systems with sub-10 nm resolution

Sergei V. Kalinin; B. J. Rodriguez; S. Jesse; T. Thundat; A. Gruverman

doi:10.1063/1.2006984

Electromechanical imaging of biological systems with sub-10 nm resolution

Sergei V. Kalinin, B. J. Rodriguez, S. Jesse, T. Thundat, A. Gruverman

Center for Nanophase Matls Sciences

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89 Scopus citations

Abstract

Electromechanical imaging of tooth dentin and enamel has been performed with sub-10 nm resolution using piezoresponse force microscopy. Characteristic piezoelectric domain size and local protein fiber ordering in dentin have been determined. The shape of a single protein fibril in enamel is visualized in real space and local hysteresis loops are measured. Because of the ubiquitous presence of piezoelectricity in biological systems, this approach is expected to find broad application in high-resolution studies of a wide range of biomaterials.

Original language	English
Article number	053901
Journal	Applied Physics Letters
Volume	87
Issue number	5
DOIs	https://doi.org/10.1063/1.2006984
State	Published - 2005

Funding

Research performed in part as a Eugene P. Wigner Fellow and staff member at the Oak Ridge National Laboratory, managed by UT-Battelle, LLC, for the U.S. Department of Energy under Contract DE-AC05-00OR22725 (for S.V.K). A.G. acknowledges financial support from the National Science Foundation (Grant No. DMR02-35632).

Funders	Funder number
National Science Foundation
U.S. Department of Energy	DE-AC05-00OR22725

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10.1063/1.2006984

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title = "Electromechanical imaging of biological systems with sub-10 nm resolution",

abstract = "Electromechanical imaging of tooth dentin and enamel has been performed with sub-10 nm resolution using piezoresponse force microscopy. Characteristic piezoelectric domain size and local protein fiber ordering in dentin have been determined. The shape of a single protein fibril in enamel is visualized in real space and local hysteresis loops are measured. Because of the ubiquitous presence of piezoelectricity in biological systems, this approach is expected to find broad application in high-resolution studies of a wide range of biomaterials.",

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AB - Electromechanical imaging of tooth dentin and enamel has been performed with sub-10 nm resolution using piezoresponse force microscopy. Characteristic piezoelectric domain size and local protein fiber ordering in dentin have been determined. The shape of a single protein fibril in enamel is visualized in real space and local hysteresis loops are measured. Because of the ubiquitous presence of piezoelectricity in biological systems, this approach is expected to find broad application in high-resolution studies of a wide range of biomaterials.

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Electromechanical imaging of biological systems with sub-10 nm resolution

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