Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters

Mariappan Parans Paranthaman; Nathan Peroutka-Bigus; Kristina R. Larsen; Kruttika S. Phadke; Tina Summers; Merlin Theodore; Dale K. Hensley; Alan M. Levine; Richard J. Lee; Bryan H. Bellaire

doi:10.1016/j.mtadv.2022.100228

Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters

Mariappan Parans Paranthaman, Nathan Peroutka-Bigus, Kristina R. Larsen, Kruttika S. Phadke, Tina Summers, Merlin Theodore, Dale K. Hensley, Alan M. Levine, Richard J. Lee, Bryan H. Bellaire

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The application of antiviral coatings to masks and respirators is a potential mitigating step toward reducing viral transmission during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The use of appropriate masks, social distancing, and vaccines is the immediate solution for limiting the viral spread and protecting people from this virus. N95 respirator masks are effective in filtering the virus particles, but they cannot kill or deactivate the virus. We report a possible approach to deactivating SARS-CoV-2 by applying an antimicrobial coating (Goldshield 75) to masks and respirators, rendering them suitable for repeated use. Masks coated with Goldshield 75 demonstrated continuous inactivation of the Alpha and Beta variants of the SARS-CoV-2 over a 3-day period and no loss of inactivation when stored at temperatures at 50 °C.

Original language	English
Article number	100228
Journal	Materials Today Advances
Volume	14
DOIs	https://doi.org/10.1016/j.mtadv.2022.100228
State	Published - Jun 2022

Funding

This research was supported by the DOE Office of Science through the National Virtual Biotechnology Laboratory (NVBL), a consortium of DOE national laboratories focused on response to COVID-19, with funding provided by the Coronavirus CARES Act and Office of Energy Efficiency and Renewable Energy, Advanced Manufacturing Office. Scanning Electron Microscopy (SEM) microstructural characterizations and Fourier Transform Infrared spectroscopy (FTIR) measurements were conducted at the Center for Nanophase Materials Sciences, which is a US Department of Energy Office of Science User Facility. Part of the coating research (MPP) was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, Materials Sciences and Engineering Division. We thank Mr. Thomas Higgins, CEO at Goldshield Technologies for providing Goldshield GS75 solution. We thank Cummins for providing materials and help with testing. This research was supported by the DOE Office of Science through the National Virtual Biotechnology Laboratory (NVBL), a consortium of DOE national laboratories focused on response to COVID-19, with funding provided by the Coronavirus CARES Act and Office of Energy Efficiency and Renewable Energy , Advanced Manufacturing Office . Scanning Electron Microscopy ( SEM ) microstructural characterizations and Fourier Transform Infrared spectroscopy ( FTIR ) measurements were conducted at the Center for Nanophase Materials Sciences, which is a US Department of Energy Office of Science User Facility. Part of the coating research (MPP) was supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, Materials Sciences and Engineering Division. We thank Mr. Thomas Higgins, CEO at Goldshield Technologies for providing Goldshield GS75 solution. We thank Cummins for providing materials and help with testing.

Keywords

Alpha and beta variants
Antiviral coatings
N95 respirator masks
SARS-CoV-2 virus deactivation
Toxicity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.mtadv.2022.100228

Cite this

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title = "Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters",

abstract = "The application of antiviral coatings to masks and respirators is a potential mitigating step toward reducing viral transmission during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The use of appropriate masks, social distancing, and vaccines is the immediate solution for limiting the viral spread and protecting people from this virus. N95 respirator masks are effective in filtering the virus particles, but they cannot kill or deactivate the virus. We report a possible approach to deactivating SARS-CoV-2 by applying an antimicrobial coating (Goldshield 75) to masks and respirators, rendering them suitable for repeated use. Masks coated with Goldshield 75 demonstrated continuous inactivation of the Alpha and Beta variants of the SARS-CoV-2 over a 3-day period and no loss of inactivation when stored at temperatures at 50 °C.",

keywords = "Alpha and beta variants, Antiviral coatings, N95 respirator masks, SARS-CoV-2 virus deactivation, Toxicity",

author = "Paranthaman, {Mariappan Parans} and Nathan Peroutka-Bigus and Larsen, {Kristina R.} and Phadke, {Kruttika S.} and Tina Summers and Merlin Theodore and Hensley, {Dale K.} and Levine, {Alan M.} and Lee, {Richard J.} and Bellaire, {Bryan H.}",

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AU - Paranthaman, Mariappan Parans

AU - Peroutka-Bigus, Nathan

AU - Larsen, Kristina R.

AU - Phadke, Kruttika S.

AU - Summers, Tina

AU - Theodore, Merlin

AU - Hensley, Dale K.

AU - Levine, Alan M.

AU - Lee, Richard J.

AU - Bellaire, Bryan H.

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AB - The application of antiviral coatings to masks and respirators is a potential mitigating step toward reducing viral transmission during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The use of appropriate masks, social distancing, and vaccines is the immediate solution for limiting the viral spread and protecting people from this virus. N95 respirator masks are effective in filtering the virus particles, but they cannot kill or deactivate the virus. We report a possible approach to deactivating SARS-CoV-2 by applying an antimicrobial coating (Goldshield 75) to masks and respirators, rendering them suitable for repeated use. Masks coated with Goldshield 75 demonstrated continuous inactivation of the Alpha and Beta variants of the SARS-CoV-2 over a 3-day period and no loss of inactivation when stored at temperatures at 50 °C.

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KW - Antiviral coatings

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Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters

Abstract

Funding

Keywords

UN SDGs

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