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DNA-polymer conjugatesviathe graft-through polymerisation of native DNA in water

  • Lucy A. Arkinstall
  • , Jonathan T. Husband
  • , Thomas R. Wilks
  • , Jeffrey C. Foster
  • , Rachel K. O'Reilly

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The direct, graft-through, ring-opening metathesis polymerisation (ROMP) of unprotected DNA macromonomers is reported. By tuning the polymerisation conditions, good control is achieved, enabling the rapid and efficient synthesis of DNA-containing bottlebrush copolymers, without the need for protection of the DNA bases.

Original languageEnglish
Pages (from-to)5466-5469
Number of pages4
JournalChemical Communications
Volume57
Issue number44
DOIs
StatePublished - Jun 4 2021
Externally publishedYes

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