Dispersion and holdup in a three-phase fluidized-bed bioreactor

Brian H. Davison

doi:10.1007/BF02936502

Dispersion and holdup in a three-phase fluidized-bed bioreactor

Brian H. Davison

Biosciences Division

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Axial dispersion and phase holdup measurements were made using electroconductivity in a fermenting fluidized-bed bioreactor (FBR) and in a model nonfermenting three-phase FBR. Multiple axial conductivity probes were used to nonintrusively monitor the bed conductivity. The gas phase holdup was estimated from a ratio of the average bed conductivity and bulk conductivity. The solid fraction in the three-phase FBR can be estimated from the two-phase liquid-solid FBR. The response to a salt pulse was used to estimate the liquid axial dispersion coefficient. Particle Peclet numbers on the order of 10^-2 were estimated as a function of flowrates and compared to literature correlations.

Original language	English
Pages (from-to)	449-460
Number of pages	12
Journal	Applied Biochemistry and Biotechnology
Volume	20-21
Issue number	1
DOIs	https://doi.org/10.1007/BF02936502
State	Published - Jan 1989

Keywords

Three-phase
columnar hydrodynamics
fermentation
fluidized-bed bioreactor

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AB - Axial dispersion and phase holdup measurements were made using electroconductivity in a fermenting fluidized-bed bioreactor (FBR) and in a model nonfermenting three-phase FBR. Multiple axial conductivity probes were used to nonintrusively monitor the bed conductivity. The gas phase holdup was estimated from a ratio of the average bed conductivity and bulk conductivity. The solid fraction in the three-phase FBR can be estimated from the two-phase liquid-solid FBR. The response to a salt pulse was used to estimate the liquid axial dispersion coefficient. Particle Peclet numbers on the order of 10-2 were estimated as a function of flowrates and compared to literature correlations.

KW - Three-phase

KW - columnar hydrodynamics

KW - fermentation

KW - fluidized-bed bioreactor

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JO - Applied Biochemistry and Biotechnology

JF - Applied Biochemistry and Biotechnology

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ER -

Dispersion and holdup in a three-phase fluidized-bed bioreactor

Abstract

Keywords

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