Abstract
We have used superinformation, which is a measure of the disorder of the entropy content of different portions of a sequence, to analyze the structural variations of the introns and exons in DNA. We have computed superinformation for the angles of the dipole moments of the base-pairs and nucleotides in the double and single-stranded forms of DNA, respectively. We show that the computed dipole-angular superinformation of the introns are significantly higher than those of the exons and that these techniques could be used for intron-exon segmentation. They also yield more accurate and computationally faster results than the previously reported methods.
Original language | English |
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Article number | 083701 |
Journal | Applied Physics Letters |
Volume | 101 |
Issue number | 8 |
DOIs | |
State | Published - Aug 20 2012 |
Externally published | Yes |