TY - GEN
T1 - Development of bacterial cellulose nanocomposites
AU - Benson, Roberto
AU - O'Neill, Hugh M.
AU - Evans, B. R.
AU - Hutchens, S.
AU - Stephens, C. P.
AU - Hammonds, R.
PY - 2011
Y1 - 2011
N2 - The development of synthetic materials with inherent bone properties would allow the safe restoration of bone function and reduce current risks associated with the use of grafts. This study investigated the development of bacterial cellulose-hydroxyapatite composite (CdHA-BC) as a potential bone substitute material. Composites of bacterial cellulose (BC) and oxidized, degradable, cellulose (OBC) were mineralized by sequential incubation in calcium chloride and aqueous sodium phosphate to form a calcium deficient hydroxyapatite (CdHA). The CdHA produced in BC and OBC is similar in morphology and chemistry to the hydroxyapatite found in natural bone. The formation of CdHA is supported by XRD, and EDS results. The CdHA-BC and CdHA-OBC composites degrade in a simulated aqueous physiological environment.
AB - The development of synthetic materials with inherent bone properties would allow the safe restoration of bone function and reduce current risks associated with the use of grafts. This study investigated the development of bacterial cellulose-hydroxyapatite composite (CdHA-BC) as a potential bone substitute material. Composites of bacterial cellulose (BC) and oxidized, degradable, cellulose (OBC) were mineralized by sequential incubation in calcium chloride and aqueous sodium phosphate to form a calcium deficient hydroxyapatite (CdHA). The CdHA produced in BC and OBC is similar in morphology and chemistry to the hydroxyapatite found in natural bone. The formation of CdHA is supported by XRD, and EDS results. The CdHA-BC and CdHA-OBC composites degrade in a simulated aqueous physiological environment.
UR - http://www.scopus.com/inward/record.url?scp=80053221151&partnerID=8YFLogxK
U2 - 10.1557/opl.2011.112
DO - 10.1557/opl.2011.112
M3 - Conference contribution
AN - SCOPUS:80053221151
SN - 9781605112893
T3 - Materials Research Society Symposium Proceedings
SP - 263
EP - 273
BT - Polymer-Based Materials and Composites - Synthesis, Assembly, Properties and Applications
T2 - 2010 MRS Fall Meeting
Y2 - 29 November 2010 through 3 December 2010
ER -