@article{ff7183d0938047b38459521f29ba11a4,
title = "Development of a high-pressure aerodynamic lens for focusing large particles (4-10 μm) into the aerosol time-of-flight mass spectrometer",
abstract = "A new aerodynamic lens system for an online aerosol time-offlight mass spectrometer (ATOFMS) has been designed and constructed to transmit and allow the analysis of individual particles in the 4-10-μm-size range. Modeling was used to help design the lens within the bounds of ATOFMS instrumental constraints. The aerodynamic lens operates at a high inlet pressure, 3066 Pa (23 Torr), with a unique tapered relaxation region to improve large particle transmission. Every stage of the lens was tested empirically using a combination of particle deposition and light scattering experiments. The critical orifice was found to significantly impact large particle transmission, with orifices <200 μm in diameter completely suppressing large particle transmission. The addition of a virtual impactor allowed for the use of large orifices without any loss of functionality in the ATOFMS. The detection efficiency of the ATOFMS was >10% for particles from 4-10 μm with a peak efficiency of 74 ± 9% for 6-μm particles. With the extended size range provided by this inlet, the ATOFMS can now be extended to investigate single cell metabolomics.",
author = "Cahill, {John F.} and Darlington, {Thomas K.} and Xiaoliang Wang and Joe Mayer and Spencer, {Matt T.} and Holecek, {John C.} and Reed, {Beth E.} and Prather, {Kimberly A.}",
note = "Publisher Copyright: Copyright {\textcopyright} American Association for Aerosol Research.",
year = "2014",
doi = "10.1080/02786826.2014.947400",
language = "English",
volume = "48",
pages = "948--956",
journal = "Aerosol Science and Technology",
issn = "0278-6826",
publisher = "Taylor and Francis Group",
number = "9",
}