Development of a DNA biochip for gene diagnosis

T. Vo-Dinh; A. L. Wintenberg; M. N. Ericson; N. Isola; J. P. Alarie

doi:10.1117/12.308046

Development of a DNA biochip for gene diagnosis

T. Vo-Dinh, A. L. Wintenberg, M. N. Ericson, N. Isola, J. P. Alarie

Sensors and Electronics

Research output: Contribution to journal › Conference article › peer-review

Abstract

We describe a biochip based on an integrated circuit photodiode array for use in medical diagnostics. The biochip is a self-contained device which has photosensors, amplifiers, discriminators and logic circuitry on board. The development and evaluation of various microchip system components of the genosensor are discussed. The performance of the DNA biochip device is illustrated with fluorescence detection of DNA probes specific to gene fragments of the human immuno-deficiency virus 1 (HIV1) system. The usefulness and potential of the DNA biochip technology for rapid and cost-effective medical diagnostics is discussed.

Original language	English
Pages (from-to)	27-33
Number of pages	7
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3253
DOIs	https://doi.org/10.1117/12.308046
State	Published - 1998
Event	Biomedical Sensing and Imaging Technologies - San Jose, CA, United States Duration: Jan 26 1998 → Jan 27 1998

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title = "Development of a DNA biochip for gene diagnosis",

abstract = "We describe a biochip based on an integrated circuit photodiode array for use in medical diagnostics. The biochip is a self-contained device which has photosensors, amplifiers, discriminators and logic circuitry on board. The development and evaluation of various microchip system components of the genosensor are discussed. The performance of the DNA biochip device is illustrated with fluorescence detection of DNA probes specific to gene fragments of the human immuno-deficiency virus 1 (HIV1) system. The usefulness and potential of the DNA biochip technology for rapid and cost-effective medical diagnostics is discussed.",

author = "T. Vo-Dinh and Wintenberg, {A. L.} and Ericson, {M. N.} and N. Isola and Alarie, {J. P.}",

year = "1998",

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note = "Biomedical Sensing and Imaging Technologies ; Conference date: 26-01-1998 Through 27-01-1998",

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AU - Vo-Dinh, T.

AU - Wintenberg, A. L.

AU - Ericson, M. N.

AU - Isola, N.

AU - Alarie, J. P.

PY - 1998

Y1 - 1998

N2 - We describe a biochip based on an integrated circuit photodiode array for use in medical diagnostics. The biochip is a self-contained device which has photosensors, amplifiers, discriminators and logic circuitry on board. The development and evaluation of various microchip system components of the genosensor are discussed. The performance of the DNA biochip device is illustrated with fluorescence detection of DNA probes specific to gene fragments of the human immuno-deficiency virus 1 (HIV1) system. The usefulness and potential of the DNA biochip technology for rapid and cost-effective medical diagnostics is discussed.

AB - We describe a biochip based on an integrated circuit photodiode array for use in medical diagnostics. The biochip is a self-contained device which has photosensors, amplifiers, discriminators and logic circuitry on board. The development and evaluation of various microchip system components of the genosensor are discussed. The performance of the DNA biochip device is illustrated with fluorescence detection of DNA probes specific to gene fragments of the human immuno-deficiency virus 1 (HIV1) system. The usefulness and potential of the DNA biochip technology for rapid and cost-effective medical diagnostics is discussed.

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U2 - 10.1117/12.308046

DO - 10.1117/12.308046

M3 - Conference article

AN - SCOPUS:0032225345

SN - 0277-786X

VL - 3253

SP - 27

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JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Biomedical Sensing and Imaging Technologies

Y2 - 26 January 1998 through 27 January 1998

ER -

Development of a DNA biochip for gene diagnosis

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