Design and performance of a new SPECT detector for multimodality small animal imaging platforms

Derek W. Austin, Michael J. Paulus, Shaun S. Gleason, Robert A. Mintzer, Stefan B. Siegel, Said D. Figueroa, Timothy J. Hoffman, Jonathan S. Wall

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

17 Scopus citations

Abstract

A new detector for single photon emission computed tomography (SPECT) has been developed for the Siemens microCAT® II and Inveon Multimodality preclinical imaging systems. The detector provides an active imaging area of 15 cm × 15 cm. We review the design of this new SPECT detector and present some key performance characteristics. Integral and differential uniformity were 3.7% and 3.0%, respectively. Mean energy resolution for 99mTc (140 keV) was 12.5%. Sensitivity as high as 1400 cps/MBq was measured for 99mTc on a dual-detector system, and a spatial resolution of 0.7 mm (FWHM) was obtained using 0.5 mm single pinhole collimators. Additionally, we present data from representative preclinical SPECT studies acquired with single and multi-pinhole collimators and multiple isotopes. Reconstructed images demonstrate that this detector is capable of high-resolution SPECT for multimodality small animal imaging.

Original languageEnglish
Title of host publication2006 IEEE Nuclear Science Symposium - Conference Record
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages3008-3011
Number of pages4
ISBN (Print)1424405610, 9781424405619
DOIs
StatePublished - 2006
Externally publishedYes
Event2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD - San Diego, CA, United States
Duration: Oct 29 2006Nov 4 2006

Publication series

NameIEEE Nuclear Science Symposium Conference Record
Volume5
ISSN (Print)1095-7863

Conference

Conference2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
Country/TerritoryUnited States
CitySan Diego, CA
Period10/29/0611/4/06

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