Design and performance of a new SPECT detector for multimodality small animal imaging platforms

Derek W. Austin, Michael J. Paulus, Shaun S. Gleason, Robert A. Mintzer, Stefan B. Siegel, Said D. Figueroa, Timothy J. Hoffman, Jonathan S. Wall

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    17 Scopus citations

    Abstract

    A new detector for single photon emission computed tomography (SPECT) has been developed for the Siemens microCAT® II and Inveon Multimodality preclinical imaging systems. The detector provides an active imaging area of 15 cm × 15 cm. We review the design of this new SPECT detector and present some key performance characteristics. Integral and differential uniformity were 3.7% and 3.0%, respectively. Mean energy resolution for 99mTc (140 keV) was 12.5%. Sensitivity as high as 1400 cps/MBq was measured for 99mTc on a dual-detector system, and a spatial resolution of 0.7 mm (FWHM) was obtained using 0.5 mm single pinhole collimators. Additionally, we present data from representative preclinical SPECT studies acquired with single and multi-pinhole collimators and multiple isotopes. Reconstructed images demonstrate that this detector is capable of high-resolution SPECT for multimodality small animal imaging.

    Original languageEnglish
    Title of host publication2006 IEEE Nuclear Science Symposium - Conference Record
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages3008-3011
    Number of pages4
    ISBN (Print)1424405610, 9781424405619
    DOIs
    StatePublished - 2006
    Event2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD - San Diego, CA, United States
    Duration: Oct 29 2006Nov 4 2006

    Publication series

    NameIEEE Nuclear Science Symposium Conference Record
    Volume5
    ISSN (Print)1095-7863

    Conference

    Conference2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
    Country/TerritoryUnited States
    CitySan Diego, CA
    Period10/29/0611/4/06

    Fingerprint

    Dive into the research topics of 'Design and performance of a new SPECT detector for multimodality small animal imaging platforms'. Together they form a unique fingerprint.

    Cite this