TY - GEN
T1 - Design and construction of a prototype rotation modulation collimator for near-field high-energy spectroscopic gamma imaging
AU - Sharma, Amy C.
AU - Tourassi, Georgia D.
AU - Kapadia, Anuj J.
AU - Harrawood, Brian P.
AU - Bender, Janelle E.
AU - Crowell, Alexander S.
AU - Kiser, Mathew R.
AU - Howell, Calvin R.
AU - Floyd, Carey E.
PY - 2006
Y1 - 2006
N2 - Neutron Stimulated Emission Computed Tomography (NSECT) is being developed for in vivo measurement of the concentration and location of biologically relevant elements. NSECT is a spectroscopic imaging technique whereby the body is illuminated via high-energy neutrons that excite elemental nuclei that then relax through characteristic gamma radiation. This imaging technique requires high-resolution spectroscopy, thereby eliminating the use conventional scintillation gamma cameras. Consequently, high-purity germanium (HPGe) semi-conductor detectors are utilized, providing no spatial information. To obtain 2D elemental concentration images, we are adapting high-energy solar spectroscopy technology. A rotating modulation collimator (RMC) consisting of two parallel-slat collimators is placed in front of the detector to modulate the incoming signal in a manner predicted by its geometry. Reconstruction of 2D images is feasible by counting the number of incident gammas at each rotation angle. The challenge is to identify a RMC geometry that allows this method to work in the near-field environment, which has far fewer assumptions and simplifications than the infinite focus of solar imaging. Herein we describe construction of a prototype RMC and experiments conducted with a radioactive 22Na point source. These experiments verified that the RMC modulates the signal in manner consistent with its geometric and physical properties.
AB - Neutron Stimulated Emission Computed Tomography (NSECT) is being developed for in vivo measurement of the concentration and location of biologically relevant elements. NSECT is a spectroscopic imaging technique whereby the body is illuminated via high-energy neutrons that excite elemental nuclei that then relax through characteristic gamma radiation. This imaging technique requires high-resolution spectroscopy, thereby eliminating the use conventional scintillation gamma cameras. Consequently, high-purity germanium (HPGe) semi-conductor detectors are utilized, providing no spatial information. To obtain 2D elemental concentration images, we are adapting high-energy solar spectroscopy technology. A rotating modulation collimator (RMC) consisting of two parallel-slat collimators is placed in front of the detector to modulate the incoming signal in a manner predicted by its geometry. Reconstruction of 2D images is feasible by counting the number of incident gammas at each rotation angle. The challenge is to identify a RMC geometry that allows this method to work in the near-field environment, which has far fewer assumptions and simplifications than the infinite focus of solar imaging. Herein we describe construction of a prototype RMC and experiments conducted with a radioactive 22Na point source. These experiments verified that the RMC modulates the signal in manner consistent with its geometric and physical properties.
UR - http://www.scopus.com/inward/record.url?scp=38649100663&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2006.354310
DO - 10.1109/NSSMIC.2006.354310
M3 - Conference contribution
AN - SCOPUS:38649100663
SN - 1424405610
SN - 9781424405619
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 2021
EP - 2024
BT - 2006 IEEE Nuclear Science Symposium - Conference Record
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2006 IEEE Nuclear Science Symposium, Medical Imaging Conference and 15th International Workshop on Room-Temperature Semiconductor X- and Gamma-Ray Detectors, Special Focus Workshops, NSS/MIC/RTSD
Y2 - 29 October 2006 through 4 November 2006
ER -