Crystallization and preliminary X-ray analysis of C-reactive protein from rat

Margaret Hopkins; Pauline A. Flanagan; Susan Bailey; Ian D. Glover; Dean A.A. Myles; Trevor J. Greenhough

doi:10.1006/jmbi.1994.1028

Crystallization and preliminary X-ray analysis of C-reactive protein from rat

Margaret Hopkins
, Pauline A. Flanagan
, Susan Bailey
, Ian D. Glover
, Dean A.A. Myles
, Trevor J. Greenhough

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Crystals of C-reactive protein from rat have been grown both with and without calcium. Two major components of the protein have been resolved on the basis of their calcium-dependent fine specificity for monophosphate esters. Crystals grown without calcium are tetragonal, space group P42₁2 with unit cell parameters a = b = 163.81(9)å and c = 125.21(6)å, and diffract X-rays to 3.0 å resolution. The rotation function specifies a molecular 5-fold symmetry axis at 24° away from c in the (110) plane.

Original language	English
Pages (from-to)	767-771
Number of pages	5
Journal	Journal of Molecular Biology
Volume	235
Issue number	2
DOIs	https://doi.org/10.1006/jmbi.1994.1028
State	Published - Jan 1994
Externally published	Yes

Keywords

C-reactive protein
Crystallization
Pentraxin
Rat

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10.1006/jmbi.1994.1028

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@article{da95cdbff01147d29824ae89239ca318,

title = "Crystallization and preliminary X-ray analysis of C-reactive protein from rat",

abstract = "Crystals of C-reactive protein from rat have been grown both with and without calcium. Two major components of the protein have been resolved on the basis of their calcium-dependent fine specificity for monophosphate esters. Crystals grown without calcium are tetragonal, space group P4212 with unit cell parameters a = b = 163.81(9){\aa} and c = 125.21(6){\aa}, and diffract X-rays to 3.0 {\aa} resolution. The rotation function specifies a molecular 5-fold symmetry axis at 24° away from c in the (110) plane.",

keywords = "C-reactive protein, Crystallization, Pentraxin, Rat",

author = "Margaret Hopkins and Flanagan, \{Pauline A.\} and Susan Bailey and Glover, \{Ian D.\} and Myles, \{Dean A.A.\} and Greenhough, \{Trevor J.\}",

year = "1994",

month = jan,

doi = "10.1006/jmbi.1994.1028",

language = "English",

volume = "235",

pages = "767--771",

journal = "Journal of Molecular Biology",

issn = "0022-2836",

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T1 - Crystallization and preliminary X-ray analysis of C-reactive protein from rat

AU - Hopkins, Margaret

AU - Flanagan, Pauline A.

AU - Bailey, Susan

AU - Glover, Ian D.

AU - Myles, Dean A.A.

AU - Greenhough, Trevor J.

PY - 1994/1

Y1 - 1994/1

N2 - Crystals of C-reactive protein from rat have been grown both with and without calcium. Two major components of the protein have been resolved on the basis of their calcium-dependent fine specificity for monophosphate esters. Crystals grown without calcium are tetragonal, space group P4212 with unit cell parameters a = b = 163.81(9)å and c = 125.21(6)å, and diffract X-rays to 3.0 å resolution. The rotation function specifies a molecular 5-fold symmetry axis at 24° away from c in the (110) plane.

AB - Crystals of C-reactive protein from rat have been grown both with and without calcium. Two major components of the protein have been resolved on the basis of their calcium-dependent fine specificity for monophosphate esters. Crystals grown without calcium are tetragonal, space group P4212 with unit cell parameters a = b = 163.81(9)å and c = 125.21(6)å, and diffract X-rays to 3.0 å resolution. The rotation function specifies a molecular 5-fold symmetry axis at 24° away from c in the (110) plane.

KW - C-reactive protein

KW - Crystallization

KW - Pentraxin

KW - Rat

UR - https://www.scopus.com/pages/publications/0028121005

U2 - 10.1006/jmbi.1994.1028

DO - 10.1006/jmbi.1994.1028

M3 - Article

AN - SCOPUS:0028121005

SN - 0022-2836

VL - 235

SP - 767

EP - 771

JO - Journal of Molecular Biology

JF - Journal of Molecular Biology

IS - 2

ER -

Crystallization and preliminary X-ray analysis of C-reactive protein from rat

Abstract

Keywords

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