Coupling the lattice-Boltzmann and spectrin-link methods for the direct numerical simulation of cellular blood flow

Daniel A. Reasor; Jonathan R. Clausen; Cyrus K. Aidun

doi:10.1002/fld.2534

Coupling the lattice-Boltzmann and spectrin-link methods for the direct numerical simulation of cellular blood flow

Daniel A. Reasor, Jonathan R. Clausen, Cyrus K. Aidun

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Abstract

The implementation of a spectrin-link (SL) red blood cell (RBC) membrane method coupled with a lattice-Boltzmann (LB) fluid solver is discussed. Details of the methodology are included along with subtleties associated with its integration into a massively parallel hybrid LB finite element (FE) suspension flow solver. A comparison of the computational performance of the coupled LB-SL method with that of the previously implemented LB-FE is given for an isolated RBC and for a dense suspension in Hagen-Poiseuille flow. Validating results for RBCs isolated in shear and parachuting in microvessel flow are also presented.

Original language	English
Pages (from-to)	767-781
Number of pages	15
Journal	International Journal for Numerical Methods in Fluids
Volume	68
Issue number	6
DOIs	https://doi.org/10.1002/fld.2534
State	Published - Feb 29 2012
Externally published	Yes

Keywords

Lattice-Boltzmann
Multiphase flow
Red blood cells
Spectrin-link modeling

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10.1002/fld.2534

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title = "Coupling the lattice-Boltzmann and spectrin-link methods for the direct numerical simulation of cellular blood flow",

abstract = "The implementation of a spectrin-link (SL) red blood cell (RBC) membrane method coupled with a lattice-Boltzmann (LB) fluid solver is discussed. Details of the methodology are included along with subtleties associated with its integration into a massively parallel hybrid LB finite element (FE) suspension flow solver. A comparison of the computational performance of the coupled LB-SL method with that of the previously implemented LB-FE is given for an isolated RBC and for a dense suspension in Hagen-Poiseuille flow. Validating results for RBCs isolated in shear and parachuting in microvessel flow are also presented.",

keywords = "Lattice-Boltzmann, Multiphase flow, Red blood cells, Spectrin-link modeling",

author = "Reasor, \{Daniel A.\} and Clausen, \{Jonathan R.\} and Aidun, \{Cyrus K.\}",

year = "2012",

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doi = "10.1002/fld.2534",

language = "English",

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pages = "767--781",

journal = "International Journal for Numerical Methods in Fluids",

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T1 - Coupling the lattice-Boltzmann and spectrin-link methods for the direct numerical simulation of cellular blood flow

AU - Reasor, Daniel A.

AU - Clausen, Jonathan R.

AU - Aidun, Cyrus K.

PY - 2012/2/29

Y1 - 2012/2/29

N2 - The implementation of a spectrin-link (SL) red blood cell (RBC) membrane method coupled with a lattice-Boltzmann (LB) fluid solver is discussed. Details of the methodology are included along with subtleties associated with its integration into a massively parallel hybrid LB finite element (FE) suspension flow solver. A comparison of the computational performance of the coupled LB-SL method with that of the previously implemented LB-FE is given for an isolated RBC and for a dense suspension in Hagen-Poiseuille flow. Validating results for RBCs isolated in shear and parachuting in microvessel flow are also presented.

AB - The implementation of a spectrin-link (SL) red blood cell (RBC) membrane method coupled with a lattice-Boltzmann (LB) fluid solver is discussed. Details of the methodology are included along with subtleties associated with its integration into a massively parallel hybrid LB finite element (FE) suspension flow solver. A comparison of the computational performance of the coupled LB-SL method with that of the previously implemented LB-FE is given for an isolated RBC and for a dense suspension in Hagen-Poiseuille flow. Validating results for RBCs isolated in shear and parachuting in microvessel flow are also presented.

KW - Lattice-Boltzmann

KW - Multiphase flow

KW - Red blood cells

KW - Spectrin-link modeling

UR - https://www.scopus.com/pages/publications/80053997907

U2 - 10.1002/fld.2534

DO - 10.1002/fld.2534

M3 - Article

AN - SCOPUS:80053997907

SN - 0271-2091

VL - 68

SP - 767

EP - 781

JO - International Journal for Numerical Methods in Fluids

JF - International Journal for Numerical Methods in Fluids

IS - 6

ER -

Coupling the lattice-Boltzmann and spectrin-link methods for the direct numerical simulation of cellular blood flow

Abstract

Keywords

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