Abstract
X-ray diffraction has been applied in measuring the helical pitch of the gramicidin channel in oriented bilayers of dilauroylphosphatidylcholine (DLPC) and dimyristoylphosphatidylcholine (DMPC) at a polypeptide concentration of 9.1 mol %. The diffraction data show the helical pitch of gramicidin to be 4.7 +/- 0.2 A in both gel and liquid-crystalline phase bilayers, with and without monovalent cations. In addition, the width of the reflection due to the pitch of the helical gramicidin channel is consistent with a five turn helix.
| Original language | English |
|---|---|
| Pages (from-to) | 827-830 |
| Number of pages | 4 |
| Journal | Biophysical Journal |
| Volume | 61 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1992 |
| Externally published | Yes |
Funding
The authors would like to thank Professors Barry M. Millman and Martha G. Shepherd for useful discussions. This research was supported by a grant from the National Sciences and Engineering Research Council of Canada.
Fingerprint
Dive into the research topics of 'Constant helical pitch of the gramicidin channel in phospholipid bilayers'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver