"click" labeling strategy for M(CO)3 (M = Re, 99mTc) prostate cancer targeted Flutamide agents

Adam L. Moore; Dejan Kreimir Buar; Leonard R. MacGillivray; Paul D. Benny

doi:10.1039/b921413e

"click" labeling strategy for M(CO)₃ (M = Re, ^99mTc) prostate cancer targeted Flutamide agents

Adam L. Moore
, Dejan Kreimir Buar
, Leonard R. MacGillivray
, Paul D. Benny

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Two distinct "click" chemistry labeling approaches were investigated with dipyridylamine alkyne derivatives and M(CO)₃ ⁺ (M = Re, ^99mTc). The triazole ring was found uncoordinated and was incorporated into the preparation of a crossover androgen receptor targeting inhibitor for prostate cancer.

Original language	English
Pages (from-to)	1926-1928
Number of pages	3
Journal	Dalton Transactions
Volume	39
Issue number	8
DOIs	https://doi.org/10.1039/b921413e
State	Published - 2010
Externally published	Yes

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10.1039/b921413e

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title = "{"}click{"} labeling strategy for M(CO)3 (M = Re, 99mTc) prostate cancer targeted Flutamide agents",

abstract = "Two distinct {"}click{"} chemistry labeling approaches were investigated with dipyridylamine alkyne derivatives and M(CO)3 + (M = Re, 99mTc). The triazole ring was found uncoordinated and was incorporated into the preparation of a crossover androgen receptor targeting inhibitor for prostate cancer.",

author = "Moore, \{Adam L.\} and Buar, \{Dejan Kreimir\} and MacGillivray, \{Leonard R.\} and Benny, \{Paul D.\}",

year = "2010",

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T1 - "click" labeling strategy for M(CO)3 (M = Re, 99mTc) prostate cancer targeted Flutamide agents

AU - Moore, Adam L.

AU - Buar, Dejan Kreimir

AU - MacGillivray, Leonard R.

AU - Benny, Paul D.

PY - 2010

Y1 - 2010

N2 - Two distinct "click" chemistry labeling approaches were investigated with dipyridylamine alkyne derivatives and M(CO)3 + (M = Re, 99mTc). The triazole ring was found uncoordinated and was incorporated into the preparation of a crossover androgen receptor targeting inhibitor for prostate cancer.

AB - Two distinct "click" chemistry labeling approaches were investigated with dipyridylamine alkyne derivatives and M(CO)3 + (M = Re, 99mTc). The triazole ring was found uncoordinated and was incorporated into the preparation of a crossover androgen receptor targeting inhibitor for prostate cancer.

UR - https://www.scopus.com/pages/publications/76749116578

U2 - 10.1039/b921413e

DO - 10.1039/b921413e

M3 - Article

C2 - 20148205

AN - SCOPUS:76749116578

SN - 1477-9226

VL - 39

SP - 1926

EP - 1928

JO - Dalton Transactions

JF - Dalton Transactions

IS - 8

ER -

"click" labeling strategy for M(CO)₃ (M = Re, ^99mTc) prostate cancer targeted Flutamide agents

Abstract

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