Characterization of underivatized pterins by laser desorption fourier transform mass spectrometry

K. Bruce Jacobson; Robert L. Hettich

doi:10.1515/pteridines.1993.4.2.72

Characterization of underivatized pterins by laser desorption fourier transform mass spectrometry

K. Bruce Jacobson, Robert L. Hettich

Bioanalytical Mass Spectrometry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)⁺ and (M + K)⁺ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more detailed structural information through an (M-H)^- ion as well as a variety of fragment ions. The collisional dissociation spectra of these negative ions give detailed structural information which is determined by possible resonance structures for the specific ions. Deuterium exchange reactions were found to be quite useful to define fragmentation pathways.

Original language	English
Pages (from-to)	72-75
Number of pages	4
Journal	Pteridines
Volume	4
Issue number	2
DOIs	https://doi.org/10.1515/pteridines.1993.4.2.72
State	Published - May 1993

Funding

This research was supported by the Office of Health and Environmental Research, U.S. Department of Energy under contract DE-AC05-840R214 00 with Martin Marietta Energy Systems, Inc.

Funders	Funder number
Office of Health and Environmental Research
U.S. Department of Energy	DE-AC05-840R214 00

Keywords

Laser desorptior
Mass spectrometry
Underivatized pterins

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10.1515/pteridines.1993.4.2.72

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year = "1993",

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AB - Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more detailed structural information through an (M-H)- ion as well as a variety of fragment ions. The collisional dissociation spectra of these negative ions give detailed structural information which is determined by possible resonance structures for the specific ions. Deuterium exchange reactions were found to be quite useful to define fragmentation pathways.

KW - Laser desorptior

KW - Mass spectrometry

KW - Underivatized pterins

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ER -

Characterization of underivatized pterins by laser desorption fourier transform mass spectrometry

Abstract

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Keywords

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