TY - JOUR
T1 - Characterization of the impact to PET quantification and image quality of an anterior array surface coil for PET/MR imaging
AU - Wollenweber, Scott D.
AU - Delso, Gaspar
AU - Deller, Timothy
AU - Goldhaber, David
AU - Hüllner, Martin
AU - Veit-Haibach, Patrick
PY - 2014/4
Y1 - 2014/4
N2 - Object: The aim of this study was to determine the impact to PET quantification, image quality and possible diagnostic impact of an anterior surface array used in a combined PET/MR imaging system. Materials and methods: An extended oval phantom and 15 whole-body FDG PET/CT subjects were re-imaged for one bed position following placement of an anterior array coil at a clinically realistic position. The CT scan, used for PET attenuation correction, did not include the coil. Comparison, including liver SUVmean, was performed between the coil present and absent images using two methods of PET reconstruction. Due to the time delay between PET scans, a model was used to account for average physiologic time change of SUV. Results: On phantom data, neglecting the coil caused a mean bias of -8.2 % for non-TOF/PSF reconstruction, and -7.3 % with TOF/PSF. On clinical data, the liver SUV neglecting the coil presence fell by -6.1 % (±6.5 %) for non-TOF/PSF reconstruction; respectively -5.2 % (±5.3 %) with TOF/PSF. All FDG-avid features seen with TOF/PSF were also seen with non-TOF/PSF reconstruction. Conclusion: Neglecting coil attenuation for this anterior array coil results in a small but significant reduction in liver SUVmean but was not found to change the clinical interpretation of the PET images.
AB - Object: The aim of this study was to determine the impact to PET quantification, image quality and possible diagnostic impact of an anterior surface array used in a combined PET/MR imaging system. Materials and methods: An extended oval phantom and 15 whole-body FDG PET/CT subjects were re-imaged for one bed position following placement of an anterior array coil at a clinically realistic position. The CT scan, used for PET attenuation correction, did not include the coil. Comparison, including liver SUVmean, was performed between the coil present and absent images using two methods of PET reconstruction. Due to the time delay between PET scans, a model was used to account for average physiologic time change of SUV. Results: On phantom data, neglecting the coil caused a mean bias of -8.2 % for non-TOF/PSF reconstruction, and -7.3 % with TOF/PSF. On clinical data, the liver SUV neglecting the coil presence fell by -6.1 % (±6.5 %) for non-TOF/PSF reconstruction; respectively -5.2 % (±5.3 %) with TOF/PSF. All FDG-avid features seen with TOF/PSF were also seen with non-TOF/PSF reconstruction. Conclusion: Neglecting coil attenuation for this anterior array coil results in a small but significant reduction in liver SUVmean but was not found to change the clinical interpretation of the PET images.
KW - Attenuation correction
KW - Magnetic resonance imaging
KW - Positron-emission tomography
UR - http://www.scopus.com/inward/record.url?scp=84898058578&partnerID=8YFLogxK
U2 - 10.1007/s10334-013-0388-1
DO - 10.1007/s10334-013-0388-1
M3 - Review article
C2 - 23800803
AN - SCOPUS:84898058578
SN - 0968-5243
VL - 27
SP - 149
EP - 159
JO - Magnetic Resonance Materials in Physics, Biology and Medicine
JF - Magnetic Resonance Materials in Physics, Biology and Medicine
IS - 2
ER -