Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices

Michael L. Simpson; Michael J. Paulus; Gerald E. Jellison; Gary S. Sayler; David E. Nivens; Hebe M. Dionisi; Steven Ripp; Bruce M. Applegate; Greg Patterson; Eric Bolton; Chris Arnott; James Rochelle

doi:10.4271/2000-01-2420

Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices

Michael L. Simpson, Michael J. Paulus, Gerald E. Jellison, Gary S. Sayler, David E. Nivens, Hebe M. Dionisi, Steven Ripp, Bruce M. Applegate, Greg Patterson, Eric Bolton, Chris Arnott, James Rochelle

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Abstract

We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our prototypes.

Original language	English
Journal	SAE Technical Papers
DOIs	https://doi.org/10.4271/2000-01-2420
State	Published - 2000
Event	30th International Conference on Environmental Systems - Toulouse, France Duration: Jul 10 2000 → Jul 13 2000

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10.4271/2000-01-2420

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@article{b29f39f978614e089e6c703f8d681656,

title = "Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices",

abstract = "We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our prototypes.",

author = "Simpson, {Michael L.} and Paulus, {Michael J.} and Jellison, {Gerald E.} and Sayler, {Gary S.} and Nivens, {David E.} and Dionisi, {Hebe M.} and Steven Ripp and Applegate, {Bruce M.} and Greg Patterson and Eric Bolton and Chris Arnott and James Rochelle",

year = "2000",

doi = "10.4271/2000-01-2420",

language = "English",

journal = "SAE Technical Papers",

issn = "0148-7191",

publisher = "SAE International",

note = "30th International Conference on Environmental Systems ; Conference date: 10-07-2000 Through 13-07-2000",

}

TY - JOUR

T1 - Bioluminescent bioreporter integrated circuits (BBICs)

T2 - 30th International Conference on Environmental Systems

AU - Simpson, Michael L.

AU - Paulus, Michael J.

AU - Jellison, Gerald E.

AU - Sayler, Gary S.

AU - Nivens, David E.

AU - Dionisi, Hebe M.

AU - Ripp, Steven

AU - Applegate, Bruce M.

AU - Patterson, Greg

AU - Bolton, Eric

AU - Arnott, Chris

AU - Rochelle, James

PY - 2000

Y1 - 2000

N2 - We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our prototypes.

AB - We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our prototypes.

UR - http://www.scopus.com/inward/record.url?scp=85072438391&partnerID=8YFLogxK

U2 - 10.4271/2000-01-2420

DO - 10.4271/2000-01-2420

M3 - Conference article

AN - SCOPUS:85072438391

SN - 0148-7191

JO - SAE Technical Papers

JF - SAE Technical Papers

Y2 - 10 July 2000 through 13 July 2000

ER -

Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices

Abstract

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