Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices 1

Michael L. Simpson; Michael J. Paulus; Gerald E. Jellison; Gary S. Sayler; Bruce M. Applegate; Steven Ripp; David E. Nivens

doi:10.4271/1999-01-2152

Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices 1

Michael L. Simpson, Michael J. Paulus, Gerald E. Jellison, Gary S. Sayler, Bruce M. Applegate, Steven Ripp, David E. Nivens

Research output: Contribution to journal › Conference article › peer-review

1 Scopus citations

Abstract

We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our early prototypes.

Original language	English
Journal	SAE Technical Papers
DOIs	https://doi.org/10.4271/1999-01-2152
State	Published - 1999
Event	29th International Conference on Environmental Systems - Denver, CO, United States Duration: Jul 12 1999 → Jul 15 1999

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10.4271/1999-01-2152

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title = "Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices 1",

abstract = "We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our early prototypes.",

author = "Simpson, {Michael L.} and Paulus, {Michael J.} and Jellison, {Gerald E.} and Sayler, {Gary S.} and Applegate, {Bruce M.} and Steven Ripp and Nivens, {David E.}",

year = "1999",

doi = "10.4271/1999-01-2152",

language = "English",

journal = "SAE Technical Papers",

issn = "0148-7191",

publisher = "SAE International",

note = "29th International Conference on Environmental Systems ; Conference date: 12-07-1999 Through 15-07-1999",

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T1 - Bioluminescent bioreporter integrated circuits (BBICs)

T2 - 29th International Conference on Environmental Systems

AU - Simpson, Michael L.

AU - Paulus, Michael J.

AU - Jellison, Gerald E.

AU - Sayler, Gary S.

AU - Applegate, Bruce M.

AU - Ripp, Steven

AU - Nivens, David E.

PY - 1999

Y1 - 1999

N2 - We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our early prototypes.

AB - We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our early prototypes.

UR - http://www.scopus.com/inward/record.url?scp=85072481324&partnerID=8YFLogxK

U2 - 10.4271/1999-01-2152

DO - 10.4271/1999-01-2152

M3 - Conference article

AN - SCOPUS:85072481324

SN - 0148-7191

JO - SAE Technical Papers

JF - SAE Technical Papers

Y2 - 12 July 1999 through 15 July 1999

ER -

Bioluminescent bioreporter integrated circuits (BBICs): Whole-cell environmental monitoring devices 1

Abstract

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