Biological Structures

Zoe Fisher; Andrew Jackson; Andrey Kovalevsky; Esko Oksanen; Hanna Wacklin

doi:10.1016/B978-0-12-805324-9.00001-7

Biological Structures

Zoe Fisher, Andrew Jackson, Andrey Kovalevsky, Esko Oksanen, Hanna Wacklin

Diffraction

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

10 Scopus citations

Abstract

Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.

Original language	English
Title of host publication	Experimental Methods in the Physical Sciences
Publisher	Academic Press
Pages	1-75
Number of pages	75
DOIs	https://doi.org/10.1016/B978-0-12-805324-9.00001-7
State	Published - 2017

Publication series

Name	Experimental Methods in the Physical Sciences
Volume	49
ISSN (Print)	1079-4042

Keywords

Crystallization
Deuteration
Macromolecular diffraction
Reflectometry
Small-angle neutron scattering

Access to Document

10.1016/B978-0-12-805324-9.00001-7

Cite this

@inbook{9e2b090d18814d10a6a6c7eb0afed8b7,

title = "Biological Structures",

abstract = "Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.",

keywords = "Crystallization, Deuteration, Macromolecular diffraction, Reflectometry, Small-angle neutron scattering",

author = "Zoe Fisher and Andrew Jackson and Andrey Kovalevsky and Esko Oksanen and Hanna Wacklin",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

doi = "10.1016/B978-0-12-805324-9.00001-7",

language = "English",

series = "Experimental Methods in the Physical Sciences",

publisher = "Academic Press",

pages = "1--75",

booktitle = "Experimental Methods in the Physical Sciences",

}

TY - CHAP

T1 - Biological Structures

AU - Fisher, Zoe

AU - Jackson, Andrew

AU - Kovalevsky, Andrey

AU - Oksanen, Esko

AU - Wacklin, Hanna

PY - 2017

Y1 - 2017

N2 - Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.

AB - Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.

KW - Crystallization

KW - Deuteration

KW - Macromolecular diffraction

KW - Reflectometry

KW - Small-angle neutron scattering

UR - http://www.scopus.com/inward/record.url?scp=85024855675&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-805324-9.00001-7

DO - 10.1016/B978-0-12-805324-9.00001-7

M3 - Chapter

AN - SCOPUS:85024855675

T3 - Experimental Methods in the Physical Sciences

SP - 1

EP - 75

BT - Experimental Methods in the Physical Sciences

PB - Academic Press

ER -

Biological Structures

Abstract

Publication series

Keywords

Access to Document

Other files and links

Fingerprint

Cite this