Biodegradable polymeric microcellular foams by modified thermally induced phase separation method

Yoon Sung Nam; Tae Gwan Park

doi:10.1016/S0142-9612(99)00073-3

Biodegradable polymeric microcellular foams by modified thermally induced phase separation method

Yoon Sung Nam, Tae Gwan Park

Research output: Contribution to journal › Article › peer-review

385 Scopus citations

Abstract

Thermally induced phase separation (TIPS) for the fabrication of porous foams based on various biodegradable polymers of poly(L-lactic acid) and its copolymers with D-lactic acid and/or glycolic acid is presented. Diverse foam morphologies were obtained by systematically changing several parameters involved in the TIPS process, such as polymer type and concentration, coarsening conditions, solvent/nonsolvent composition, and the presence of an additive. The produced foams had microcellular structures with average pore diameters ranging from 1 to 30μm depending on the process parameters, which were characterized by scanning electron microscopy (SEM) and mercury intrusion porosimetry. Additionally, Pluronic F127 was used as an additive porogen to control the pore geometry and size. Copyright (C) 1999 Elsevier Science Ltd.

Original language	English
Pages (from-to)	1783-1790
Number of pages	8
Journal	Biomaterials
Volume	20
Issue number	19
DOIs	https://doi.org/10.1016/S0142-9612(99)00073-3
State	Published - Oct 1999
Externally published	Yes

Keywords

Biodegradable polymers
Foams
Poly(L-lactic acid)
Thermally induced phase separation
Tissue engineering

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10.1016/S0142-9612(99)00073-3

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title = "Biodegradable polymeric microcellular foams by modified thermally induced phase separation method",

abstract = "Thermally induced phase separation (TIPS) for the fabrication of porous foams based on various biodegradable polymers of poly(L-lactic acid) and its copolymers with D-lactic acid and/or glycolic acid is presented. Diverse foam morphologies were obtained by systematically changing several parameters involved in the TIPS process, such as polymer type and concentration, coarsening conditions, solvent/nonsolvent composition, and the presence of an additive. The produced foams had microcellular structures with average pore diameters ranging from 1 to 30μm depending on the process parameters, which were characterized by scanning electron microscopy (SEM) and mercury intrusion porosimetry. Additionally, Pluronic F127 was used as an additive porogen to control the pore geometry and size. Copyright (C) 1999 Elsevier Science Ltd.",

keywords = "Biodegradable polymers, Foams, Poly(L-lactic acid), Thermally induced phase separation, Tissue engineering",

author = "Nam, {Yoon Sung} and Park, {Tae Gwan}",

year = "1999",

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T1 - Biodegradable polymeric microcellular foams by modified thermally induced phase separation method

AU - Nam, Yoon Sung

AU - Park, Tae Gwan

PY - 1999/10

Y1 - 1999/10

N2 - Thermally induced phase separation (TIPS) for the fabrication of porous foams based on various biodegradable polymers of poly(L-lactic acid) and its copolymers with D-lactic acid and/or glycolic acid is presented. Diverse foam morphologies were obtained by systematically changing several parameters involved in the TIPS process, such as polymer type and concentration, coarsening conditions, solvent/nonsolvent composition, and the presence of an additive. The produced foams had microcellular structures with average pore diameters ranging from 1 to 30μm depending on the process parameters, which were characterized by scanning electron microscopy (SEM) and mercury intrusion porosimetry. Additionally, Pluronic F127 was used as an additive porogen to control the pore geometry and size. Copyright (C) 1999 Elsevier Science Ltd.

AB - Thermally induced phase separation (TIPS) for the fabrication of porous foams based on various biodegradable polymers of poly(L-lactic acid) and its copolymers with D-lactic acid and/or glycolic acid is presented. Diverse foam morphologies were obtained by systematically changing several parameters involved in the TIPS process, such as polymer type and concentration, coarsening conditions, solvent/nonsolvent composition, and the presence of an additive. The produced foams had microcellular structures with average pore diameters ranging from 1 to 30μm depending on the process parameters, which were characterized by scanning electron microscopy (SEM) and mercury intrusion porosimetry. Additionally, Pluronic F127 was used as an additive porogen to control the pore geometry and size. Copyright (C) 1999 Elsevier Science Ltd.

KW - Biodegradable polymers

KW - Foams

KW - Poly(L-lactic acid)

KW - Thermally induced phase separation

KW - Tissue engineering

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U2 - 10.1016/S0142-9612(99)00073-3

DO - 10.1016/S0142-9612(99)00073-3

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AN - SCOPUS:0032874505

SN - 0142-9612

VL - 20

SP - 1783

EP - 1790

JO - Biomaterials

JF - Biomaterials

IS - 19

ER -

Biodegradable polymeric microcellular foams by modified thermally induced phase separation method

Abstract

Keywords

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