Biodegradable polymer nanocylinders fabricated by transverse fragmentation of electrospun nanofibers through aminolysis

Taek Gyoung Kim; Tae Gwan Park

doi:10.1002/marc.200800094

Biodegradable polymer nanocylinders fabricated by transverse fragmentation of electrospun nanofibers through aminolysis

Taek Gyoung Kim, Tae Gwan Park

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

Biodegradable polymeric nanocylinders were fabricated by segmental degradation of electrospun nanofibers. Poly(L-lactic acid) (PLA) was electrospun to produce non-crystalline nanofibers that were immediately treated with amino group-containing strong bases to fabricate semicrystalline PLA nanocylinders with tunable aspect ratio. The formation of PLA nanocylinders was attributed to two concurrent events occurring during the aminolysis reaction: (i) development of stacked lamellae and (ii) transversely oriented degradation and fragmentation of the amorphous gaps between lamellae, both responsible for the fragmentation of PLA nanofibers into uniformly shaped nanocylinders. The aspect ratio of PLA nanocylinders was tunable by varying aminolysis time and controlling nanofiber diameter.

Original language	English
Pages (from-to)	1231-1236
Number of pages	6
Journal	Macromolecular Rapid Communications
Volume	29
Issue number	14
DOIs	https://doi.org/10.1002/marc.200800094
State	Published - Jul 16 2008
Externally published	Yes

Keywords

Biodegradable
Crystallization
Electrospinning
Poly-lactic acid
Polymer nanocylinders

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10.1002/marc.200800094

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title = "Biodegradable polymer nanocylinders fabricated by transverse fragmentation of electrospun nanofibers through aminolysis",

abstract = "Biodegradable polymeric nanocylinders were fabricated by segmental degradation of electrospun nanofibers. Poly(L-lactic acid) (PLA) was electrospun to produce non-crystalline nanofibers that were immediately treated with amino group-containing strong bases to fabricate semicrystalline PLA nanocylinders with tunable aspect ratio. The formation of PLA nanocylinders was attributed to two concurrent events occurring during the aminolysis reaction: (i) development of stacked lamellae and (ii) transversely oriented degradation and fragmentation of the amorphous gaps between lamellae, both responsible for the fragmentation of PLA nanofibers into uniformly shaped nanocylinders. The aspect ratio of PLA nanocylinders was tunable by varying aminolysis time and controlling nanofiber diameter.",

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AU - Kim, Taek Gyoung

AU - Park, Tae Gwan

PY - 2008/7/16

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N2 - Biodegradable polymeric nanocylinders were fabricated by segmental degradation of electrospun nanofibers. Poly(L-lactic acid) (PLA) was electrospun to produce non-crystalline nanofibers that were immediately treated with amino group-containing strong bases to fabricate semicrystalline PLA nanocylinders with tunable aspect ratio. The formation of PLA nanocylinders was attributed to two concurrent events occurring during the aminolysis reaction: (i) development of stacked lamellae and (ii) transversely oriented degradation and fragmentation of the amorphous gaps between lamellae, both responsible for the fragmentation of PLA nanofibers into uniformly shaped nanocylinders. The aspect ratio of PLA nanocylinders was tunable by varying aminolysis time and controlling nanofiber diameter.

AB - Biodegradable polymeric nanocylinders were fabricated by segmental degradation of electrospun nanofibers. Poly(L-lactic acid) (PLA) was electrospun to produce non-crystalline nanofibers that were immediately treated with amino group-containing strong bases to fabricate semicrystalline PLA nanocylinders with tunable aspect ratio. The formation of PLA nanocylinders was attributed to two concurrent events occurring during the aminolysis reaction: (i) development of stacked lamellae and (ii) transversely oriented degradation and fragmentation of the amorphous gaps between lamellae, both responsible for the fragmentation of PLA nanofibers into uniformly shaped nanocylinders. The aspect ratio of PLA nanocylinders was tunable by varying aminolysis time and controlling nanofiber diameter.

KW - Biodegradable

KW - Crystallization

KW - Electrospinning

KW - Poly-lactic acid

KW - Polymer nanocylinders

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JO - Macromolecular Rapid Communications

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Biodegradable polymer nanocylinders fabricated by transverse fragmentation of electrospun nanofibers through aminolysis

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