AtRGS1 function in Arabidopsis thaliana

Jin Gui Chen; Alan M. Jones

doi:10.1016/S0076-6879(04)89020-7

AtRGS1 function in Arabidopsis thaliana

Jin Gui Chen, Alan M. Jones

Research output: Contribution to journal › Article › peer-review

119 Scopus citations

Abstract

Arabidopsis thaliana RGS1 is a novel "regulator of G-protein signaling" (AtRGS1) protein that consists of an N-terminal seven transmembrane domain characteristic of G-protein-coupled receptors and a C-terminal RGS box. AtRGS1 modulates plant cell proliferation. Atrgs1 mutants are insensitive to glucose and less sensitive to fructose and sucrose, suggesting that sugar signaling in Arabidopsis involves AtRGS1. In addition, sugar metabolism and phosphorylation by hexokinase (HXK) are not required for AtRGS1-mediated sugar signaling, suggesting that AtRGS1 functions in a HXK-independent glucose signaling pathway.

Original language	English
Pages (from-to)	338-350
Number of pages	13
Journal	Methods in Enzymology
Volume	389
DOIs	https://doi.org/10.1016/S0076-6879(04)89020-7
State	Published - 2004
Externally published	Yes

Funding

Work in A.M.J.'s laboratory on the Arabidopsis G protein is supported by the NIH (GM65989-01) and NSF (MCB-0209711).

Funders	Funder number
National Science Foundation	MCB-0209711
National Institutes of Health	GM65989-01
National Institute of General Medical Sciences	R01GM065989

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AB - Arabidopsis thaliana RGS1 is a novel "regulator of G-protein signaling" (AtRGS1) protein that consists of an N-terminal seven transmembrane domain characteristic of G-protein-coupled receptors and a C-terminal RGS box. AtRGS1 modulates plant cell proliferation. Atrgs1 mutants are insensitive to glucose and less sensitive to fructose and sucrose, suggesting that sugar signaling in Arabidopsis involves AtRGS1. In addition, sugar metabolism and phosphorylation by hexokinase (HXK) are not required for AtRGS1-mediated sugar signaling, suggesting that AtRGS1 functions in a HXK-independent glucose signaling pathway.

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ER -

AtRGS1 function in Arabidopsis thaliana

Abstract

Funding

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