Abstract
Three dimensional (3D) supramolecules with giant cavities are attractive due to their wide range of applications. Herein, we used pentatopic terpyridine ligands with three types of coordination moieties to assemble two giant supramolecular hexagonal prisms with a molecular weight up to 42 »608 and 43 »569 Da, respectively. Within the prisms, two double-rimmed Kandinsky Circles serve as the base surfaces as well as the templates for assisting the self-sorting during the self-assembly. Additionally, hierarchical self-assembly of these supramolecular prisms into tubular-like nanostructures was fully studied by scanning tunneling microscopy (STM) and small-angle X-ray scattering (SAXS). Finally, these supramolecular prisms show good antimicrobial activities against Gram-positive pathogen methicillin-resistant Staphylococcus aureus (MRSA) and Bacillus subtilis (B. subtilis).
| Original language | English |
|---|---|
| Pages (from-to) | 16108-16116 |
| Number of pages | 9 |
| Journal | Journal of the American Chemical Society |
| Volume | 141 |
| Issue number | 40 |
| DOIs | |
| State | Published - Oct 9 2019 |
| Externally published | Yes |
Funding
We acknowledge the support from NIH (R01GM128037 to X.L.; 5R01AL110098-05 to B.X; and R35GM133617 to P.E.), and partial support through University of South Florida Nexus Initiative (UNI) Award. The SAXS data were collected with the help of Dr. Lin Yang, at the 16ID-LiX Beamline, National Synchrotron Light Source II, Brookhaven National Laboratory (BNL), NY, USA, through a beamtime proposal (BAG-302208). The LiX beamline is part of the Life Science Biomedical Technology Research resource, jointly supported by the National Institutes of Health, National Institute of General Medical Sciences, under Grant P41 GM111244, and by the Department of Energy Office of Biological and Environmental Research under Grant KP1605010, with additional support from NIH Grant S10 OD012331. NSLS-II is a U.S. Department of Energy (DOE) Office of Science User Facility, operated for the DOE Office of Science by Brookhaven National Laboratory under Contract No. DE-SC0012704.
