TY - JOUR
T1 - Artemisia and Artemisia-based products for COVID-19 management
T2 - current state and future perspective
AU - Orege, Joshua Iseoluwa
AU - Adeyemi, Sherif Babatunde
AU - Tiamiyu, Bashir Bolaji
AU - Akinyemi, Toluwanimi Oluwadara
AU - Ibrahim, Yusuf Ajibola
AU - Orege, Odunola Blessing
N1 - Publisher Copyright:
© 2021, Institute of Korean Medicine, Kyung Hee University.
PY - 2023/3
Y1 - 2023/3
N2 - The search for a potent anti-coronavirus therapy for severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) remains an overwhelming task since the outbreak of COVID-19. It is more evident that most of the existing antiviral and immune-boosting drugs are non-promising and ineffective for the treatment of coronavirus infected patients while the safety of a few drugs/vaccines that have demonstrated high potential remains unclear. With daily records of confirmed infectious cases across the world, it is crucial to emphasize the need for repurposed therapies with a validated ethnomedicinal base focused on well-known active medicines with traceable biochemical, pharmacological and safety profiles for viral infection management. In the present study, recent literature on Artemisia and Artemisia-based products for the management of COVID-19 are reviewed. Artemisia-based products have demonstrated a broad spectrum of biological ability including antiviral properties. Besides its antiviral activity, Artemisia annua have shown to contain appreciable amounts of minerals such as zinc, gallium and selenium among others. Graphic abstract: [Figure not available: see fulltext.].
AB - The search for a potent anti-coronavirus therapy for severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) remains an overwhelming task since the outbreak of COVID-19. It is more evident that most of the existing antiviral and immune-boosting drugs are non-promising and ineffective for the treatment of coronavirus infected patients while the safety of a few drugs/vaccines that have demonstrated high potential remains unclear. With daily records of confirmed infectious cases across the world, it is crucial to emphasize the need for repurposed therapies with a validated ethnomedicinal base focused on well-known active medicines with traceable biochemical, pharmacological and safety profiles for viral infection management. In the present study, recent literature on Artemisia and Artemisia-based products for the management of COVID-19 are reviewed. Artemisia-based products have demonstrated a broad spectrum of biological ability including antiviral properties. Besides its antiviral activity, Artemisia annua have shown to contain appreciable amounts of minerals such as zinc, gallium and selenium among others. Graphic abstract: [Figure not available: see fulltext.].
KW - Anti-inflammation
KW - Artemisia
KW - Artemisia derivatives
KW - Clinical trials
KW - COVID-19
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85105501508&partnerID=8YFLogxK
U2 - 10.1007/s13596-021-00576-5
DO - 10.1007/s13596-021-00576-5
M3 - Review article
AN - SCOPUS:85105501508
SN - 2662-4052
VL - 23
SP - 85
EP - 96
JO - Advances in Traditional Medicine
JF - Advances in Traditional Medicine
IS - 1
ER -