An atlas-based organ dose estimator for tomosynthesis and radiography

Jocelyn Hoye; Yakun Zhang; Greeshma Agasthya; Greg Sturgeon; Anuj Kapadia; W. Paul Segars; Ehsan Samei

doi:10.1117/12.2255583

An atlas-based organ dose estimator for tomosynthesis and radiography

Jocelyn Hoye, Yakun Zhang, Greeshma Agasthya, Greg Sturgeon, Anuj Kapadia, W. Paul Segars, Ehsan Samei

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The purpose of this study was to provide patient-specific organ dose estimation based on an atlas of human models for twenty tomosynthesis and radiography protocols. The study utilized a library of 54 adult computational phantoms (age: 18-78 years, weight 52-117 kg) and a validated Monte-Carlo simulation (PENELOPE) of a tomosynthesis and radiography system to estimate organ dose. Positioning of patient anatomy was based on radiographic positioning handbooks. The field of view for each exam was calculated to include relevant organs per protocol. Through simulations, the energy deposited in each organ was binned to estimate normalized organ doses into a reference database. The database can be used as the basis to devise a dose calculator to predict patient-specific organ dose values based on kVp, mAs, exposure in air, and patient habitus for a given protocol. As an example of the utility of this tool, dose to an organ was studied as a function of average patient thickness in the field of view for a given exam and as a function of Body Mass Index (BMI). For tomosynthesis, organ doses can also be studied as a function of x-ray tube position. This work developed comprehensive information for organ dose dependencies across tomosynthesis and radiography. There was a general exponential decrease dependency with increasing patient size that is highly protocol dependent. There was a wide range of variability in organ dose across the patient population, which needs to be incorporated in the metrology of organ dose.

Original language	English
Title of host publication	Medical Imaging 2017
Subtitle of host publication	Physics of Medical Imaging
Editors	Taly Gilat Schmidt, Joseph Y. Lo, Thomas G. Flohr
Publisher	SPIE
ISBN (Electronic)	9781510607095
DOIs	https://doi.org/10.1117/12.2255583
State	Published - 2017
Externally published	Yes
Event	Medical Imaging 2017: Physics of Medical Imaging - Orlando, United States Duration: Feb 13 2017 → Feb 16 2017

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10132
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2017: Physics of Medical Imaging
Country/Territory	United States
City	Orlando
Period	02/13/17 → 02/16/17

Keywords

Dose
Dose calculator
Monte Carlo
Patient-specific
Radiation
Radiography
Tomosynthesis

Access to Document

10.1117/12.2255583

Cite this

Hoye, J., Zhang, Y., Agasthya, G., Sturgeon, G., Kapadia, A., Segars, W. P., & Samei, E. (2017). An atlas-based organ dose estimator for tomosynthesis and radiography. In T. G. Schmidt, J. Y. Lo, & T. G. Flohr (Eds.), Medical Imaging 2017: Physics of Medical Imaging Article 1013204 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10132). SPIE. https://doi.org/10.1117/12.2255583

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title = "An atlas-based organ dose estimator for tomosynthesis and radiography",

abstract = "The purpose of this study was to provide patient-specific organ dose estimation based on an atlas of human models for twenty tomosynthesis and radiography protocols. The study utilized a library of 54 adult computational phantoms (age: 18-78 years, weight 52-117 kg) and a validated Monte-Carlo simulation (PENELOPE) of a tomosynthesis and radiography system to estimate organ dose. Positioning of patient anatomy was based on radiographic positioning handbooks. The field of view for each exam was calculated to include relevant organs per protocol. Through simulations, the energy deposited in each organ was binned to estimate normalized organ doses into a reference database. The database can be used as the basis to devise a dose calculator to predict patient-specific organ dose values based on kVp, mAs, exposure in air, and patient habitus for a given protocol. As an example of the utility of this tool, dose to an organ was studied as a function of average patient thickness in the field of view for a given exam and as a function of Body Mass Index (BMI). For tomosynthesis, organ doses can also be studied as a function of x-ray tube position. This work developed comprehensive information for organ dose dependencies across tomosynthesis and radiography. There was a general exponential decrease dependency with increasing patient size that is highly protocol dependent. There was a wide range of variability in organ dose across the patient population, which needs to be incorporated in the metrology of organ dose.",

keywords = "Dose, Dose calculator, Monte Carlo, Patient-specific, Radiation, Radiography, Tomosynthesis",

author = "Jocelyn Hoye and Yakun Zhang and Greeshma Agasthya and Greg Sturgeon and Anuj Kapadia and Segars, {W. Paul} and Ehsan Samei",

note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; Medical Imaging 2017: Physics of Medical Imaging ; Conference date: 13-02-2017 Through 16-02-2017",

year = "2017",

doi = "10.1117/12.2255583",

language = "English",

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Hoye, J, Zhang, Y, Agasthya, G, Sturgeon, G, Kapadia, A, Segars, WP & Samei, E 2017, An atlas-based organ dose estimator for tomosynthesis and radiography. in TG Schmidt, JY Lo & TG Flohr (eds), Medical Imaging 2017: Physics of Medical Imaging., 1013204, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10132, SPIE, Medical Imaging 2017: Physics of Medical Imaging, Orlando, United States, 02/13/17. https://doi.org/10.1117/12.2255583

An atlas-based organ dose estimator for tomosynthesis and radiography. / Hoye, Jocelyn; Zhang, Yakun; Agasthya, Greeshma et al.
Medical Imaging 2017: Physics of Medical Imaging. ed. / Taly Gilat Schmidt; Joseph Y. Lo; Thomas G. Flohr. SPIE, 2017. 1013204 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10132).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Zhang, Yakun

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AU - Segars, W. Paul

AU - Samei, Ehsan

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AB - The purpose of this study was to provide patient-specific organ dose estimation based on an atlas of human models for twenty tomosynthesis and radiography protocols. The study utilized a library of 54 adult computational phantoms (age: 18-78 years, weight 52-117 kg) and a validated Monte-Carlo simulation (PENELOPE) of a tomosynthesis and radiography system to estimate organ dose. Positioning of patient anatomy was based on radiographic positioning handbooks. The field of view for each exam was calculated to include relevant organs per protocol. Through simulations, the energy deposited in each organ was binned to estimate normalized organ doses into a reference database. The database can be used as the basis to devise a dose calculator to predict patient-specific organ dose values based on kVp, mAs, exposure in air, and patient habitus for a given protocol. As an example of the utility of this tool, dose to an organ was studied as a function of average patient thickness in the field of view for a given exam and as a function of Body Mass Index (BMI). For tomosynthesis, organ doses can also be studied as a function of x-ray tube position. This work developed comprehensive information for organ dose dependencies across tomosynthesis and radiography. There was a general exponential decrease dependency with increasing patient size that is highly protocol dependent. There was a wide range of variability in organ dose across the patient population, which needs to be incorporated in the metrology of organ dose.

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KW - Monte Carlo

KW - Patient-specific

KW - Radiation

KW - Radiography

KW - Tomosynthesis

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ER -

An atlas-based organ dose estimator for tomosynthesis and radiography

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Keywords

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