Abstract
This paper reviews age-specific biokinetic data for iodine in humans and extends to pre-adult ages the baseline parameter values of the author's previously published model for systemic iodine in adult humans. Compared with the ICRP's current age-specific model for iodine introduced in Publication 56 (1989, pp 45-48), the present model provides a more detailed description of the behaviour of iodine in the human body; predicts moderately higher doses to the thyroid for short-lived isotopes of iodine; predicts similar doses to the thyroid for isotopes with half-time greater than a few hours; and, for most iodine isotopes, predicts substantially higher doses to salivary glands, stomach wall, liver, and kidneys.
| Original language | English |
|---|---|
| Pages (from-to) | 864-882 |
| Number of pages | 19 |
| Journal | Journal of Radiological Protection |
| Volume | 37 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2017 |
Funding
The work described in this manuscript was sponsored by the Centers for Disease Control and Prevention (CDC) Office of Noncommunicable Diseases, Injury and Environmental Health, National Center for Environmental Health, under Interagency Agreement DOE No. 2220-Z051-16, and by the Office of Radiation and Indoor Air, US Environmental Protection Agency (EPA), under Interagency Agreement DOE No. 1824 S581-A1, under contract No. DE-AC05-00OR22725 with UT-Battelle.
Keywords
- age-specific
- biokinetics
- iodine
- model