Alignable biomimetic membranes

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Abstract

Using neutron diffraction, we have recently shown that lipid bilayers doped with paramagnetic lanthanide ions are highly alignable (≤ 1.0° mosaic) in a magnetic field and give rise to distinct Bragg reflections (h = 5) indicative of a smectic mesophase. In addition, using rigid substrates, we have succeeded for the first time in aligning (≤ 0.5° mosaic) membrane systems under conditions of excess water. These two methods of aligning biomolecules will enable a variety of systems to be studied under physiologically relevant conditions.

Original languageEnglish
Pages (from-to)1178-1180
Number of pages3
JournalPhysica B: Physics of Condensed Matter
Volume241-243
DOIs
StatePublished - 1997
Externally publishedYes

Keywords

  • Excess water condition
  • Lipid multibilayers
  • Magnetically alignable bilayers
  • Mechanically aligned bilayers

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