Aggregation structure of DNA-conjugated gold nanoparticles

Shizuto Yamakoshi, Yasuhiro Sakai, Kohzo Ito, Yuuya Shinohara, Yoshiyuki Amemiya, Naoki Kanayama, Tohru Takarada, Mizuo Maeda

Research output: Contribution to conferencePaperpeer-review

Abstract

DNA-conjugated gold nanoparticles exhibit a unique aggregation behavior that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form.This suggests that the ends of completely double-strand DNA conjugated on gold nanoparticles contact or interdigitate slightly with each other in the aggeregation structure.

Original languageEnglish
Pages2178
Number of pages1
StatePublished - 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006

Conference

Conference55th SPSJ Annual Meeting
Country/TerritoryJapan
CityNagoya
Period05/24/0605/26/06

Keywords

  • Colloid
  • DNA
  • Gold nanoparticles
  • SAXS
  • SNPs
  • Structure of aggregate

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