TY - JOUR
T1 - Accurate molecular structures of chlorothiazide and hydrochlorothiazide by joint refinement against powder neutron and X-ray diffraction data
AU - Leech, Charlotte K.
AU - Fabbiani, Francesca P.A.
AU - Shankland, Kenneth
AU - David, William I.F.
AU - Ibberson, Richard M.
PY - 2008/1/17
Y1 - 2008/1/17
N2 - The compounds chlorothiazide and hydrochlorothiazide (crystalline form II) have been studied in their fully hydrogenous forms by powder neutron diffraction on the GEM diffractometer. The results of joint Rietveld refinement of the structures against multi-bank neutron and single-bank X-ray powder data are reported and show that accurate and precise structural information can be obtained from polycrystalline molecular organic materials by this route.
AB - The compounds chlorothiazide and hydrochlorothiazide (crystalline form II) have been studied in their fully hydrogenous forms by powder neutron diffraction on the GEM diffractometer. The results of joint Rietveld refinement of the structures against multi-bank neutron and single-bank X-ray powder data are reported and show that accurate and precise structural information can be obtained from polycrystalline molecular organic materials by this route.
UR - http://www.scopus.com/inward/record.url?scp=38749096685&partnerID=8YFLogxK
U2 - 10.1107/S010876810705687X
DO - 10.1107/S010876810705687X
M3 - Article
C2 - 18204216
AN - SCOPUS:38749096685
SN - 0108-7681
VL - 64
SP - 101
EP - 107
JO - Acta Crystallographica Section B: Structural Science
JF - Acta Crystallographica Section B: Structural Science
IS - 1
ER -